Osteoarthritis (OA) is associated with cartilage destruction, subchondral bone remodeling
and inflammation of the synovial membrane, although the etiology and pathogenesis …

Osteoarthritis is a painful and disabling disease that affects millions of patients. Its aetiology
is largely unknown, but is most likely multi-factorial. Osteoarthritis poses a dilemma: it often …

Osteoarthritis (OA), the most common form of arthritis, is a debilitating and progressive
disease that has become a major cause of disability and impaired quality of life in the …

Knee osteoarthritis remains a tremendous public health concern, both in terms of health‐
related quality of life and financial burden of disease. Translational research is a critical step …

AIM: The primary goal of this body of work is to suggest a standardized system for
histopathological assessment of experimental surgical instability models of osteoarthritis …

Bisphosphonates have been proposed as possible disease-modifying drugs in
osteoarthritis. However, the evidence of their efficacy is poor and their outcomes presented a …

Contemporary treatments for osteoarthritis (OA) pursue only to alleviate the pain caused by
the illness. Discovering disease-modifying osteoarthritis drugs (DMOADs) that can induce …

Purpose of review: The recent literature on the factors that initiate and accelerate the
progression of osteoarthritis following ligament injuries and their treatment is reviewed …

Objective To evaluate the relationships among cartilage and subchondral bone before and
after the onset of cartilage degeneration in the Hartley guinea pig model of spontaneous …

Objectives. To determine whether risedronate (RIS) slows down trabecular bone loss in the
medial compartment of the proximal tibia, a characteristic of patients with progressive knee …