Macrolide resistance mechanisms can be target-based with a change in a 23S ribosomal
RNA (rRNA) residue or a mutation in ribosomal protein L4 or L22 affecting the ribosome's …

ECOLOGY The scope of mycoplasmology has been con-siderably widened during the last
few years. Not only has the total number of species been brought to over 60 (329), but …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

In recent years, Mycoplasma pneumoniae strains that are clinically resistant to macrolide
antibiotics have occasionally been encountered in Japan. Of 76 strains of M. pneumoniae …

Preterm birth is the leading cause of neonatal morbidity and mortality worldwide, and the
human Ureaplasma species are most frequently isolated from the amniotic fluid and …

Mycoplasma pneumoniae is a pathogenic mycoplasma responsible for respiratory tract
infections in humans, which occurs worldwide in children and adults. This article focuses on …

▪ Abstract Antibiotics target ribosomes at distinct locations within functionally relevant sites.
They exert their inhibitory action by diverse modes, including competing with substrate …

Mycoplasma hominis is an opportunistic human mycoplasma. Two other pathogenic human
species, M. genitalium and Ureaplasma parvum, reside within the same natural niche as M …

Macrolide-resistant mutants of Mycoplasma pneumoniae were selected in vitro from the
susceptible reference strain M129, by 23 to 50 serial passages in subinhibitory …

Background The bacterial ribosome is a primary target of several classes of antibiotics.
Investigation of the structure of the ribosomal subunits in complex with different antibiotics …