Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles

R Mohammadinejad, MA Moosavi, S Tavakol… - Autophagy, 2019 - Taylor & Francis
Nanomaterials have gained a rapid increase in use in a variety of applications that pertain to
many aspects of human life. The majority of these innovations are centered on medical …

Survivin: a unique target for tumor therapy

H Garg, P Suri, JC Gupta, GP Talwar, S Dubey - Cancer cell international, 2016 - Springer
Survivin is the smallest member of the Inhibitor of apoptosis (IAP) family of proteins, involved
in inhibition of apoptosis and regulation of cell cycle. These functional attributes make …

Targeting IAP proteins for therapeutic intervention in cancer

S Fulda, D Vucic - Nature reviews Drug discovery, 2012 - nature.com
Evasion of apoptosis is one of the crucial acquired capabilities used by cancer cells to fend
off anticancer therapies. Inhibitor of apoptosis (IAP) proteins exert a range of biological …

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

G Ambrosini, C Adida, DC Altieri - Nature medicine, 1997 - nature.com
Inhibitors of programmed cell death (apoptosis) aberrantly prolonging cell viability may
contribute to cancer1 by facilitating the insurgence of mutations and by promoting resistance …

IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer

M Gyrd-Hansen, P Meier - Nature Reviews Cancer, 2010 - nature.com
The realization that alterations in inhibitor of apoptosis (IAP) proteins are found in many
types of human cancer and are associated with chemoresistance, disease progression and …

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

WC Earnshaw, LM Martins… - Annual review of …, 1999 - annualreviews.org
▪ Abstract Apoptosis is a genetically programmed, morphologically distinct form of cell death
that can be triggered by a variety of physiological and pathological stimuli. Studies …

IAP family proteins—suppressors of apoptosis

QL Deveraux, JC Reed - Genes & development, 1999 - genesdev.cshlp.org
Apoptosis is a physiological cell suicide program that is critical for the development and
maintenance of healthy tissues. Dysregulation of cell death pathways occur in cancer …

[HTML][HTML] Recent advances in apoptosis, mitochondria and drug resistance in cancer cells

IR Indran, G Tufo, S Pervaiz, C Brenner - Biochimica et Biophysica Acta …, 2011 - Elsevier
Defective or inefficient apoptosis is an acquired hallmark of cancer cells. Thus, a thorough
understanding of apoptotic signaling pathways and insights into apoptosis resistance …

IAP proteins: blocking the road to death's door

GS Salvesen, CS Duckett - Nature reviews Molecular cell biology, 2002 - nature.com
The'inhibitor of apoptosis'(IAP) gene family, which was discovered less than a decade ago,
encodes a group of structurally related proteins that, in addition to their ability to suppress …

Baculovirus molecular biology

GF Rohrmann - 2019 - ir.library.oregonstate.edu
This is the 4th edition of a book that was initiated with the annotation of the function of all the
genes in the most commonly studied baculovirus, AcMNPV. It has been almost six years …