Synthetic glycans to improve current glycoconjugate vaccines and fight antimicrobial resistance

L Del Bino, KE Østerlid, DY Wu, F Nonne… - Chemical …, 2022 - ACS Publications
Antimicrobial resistance (AMR) is emerging as the next potential pandemic. Different
microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides difficile …

Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections

Y Wu, D Battalapalli, MJ Hakeem, V Selamneni… - Journal of …, 2021 - Springer
Antibiotic resistance is spreading rapidly around the world and seriously impeding efforts to
control microbial infections. Although nucleic acid testing is widely deployed for the …

[HTML][HTML] The role of bacterial ATP-binding cassette (ABC) transporters in pathogenesis and virulence: Therapeutic and vaccine potential

AA Akhtar, DPJ Turner - Microbial pathogenesis, 2022 - Elsevier
The ATP-binding cassette (ABC) transporter superfamily is found in all domains of life,
facilitating critical biological processes through the translocation of a wide variety of …

β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium

JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Potentials of nanotechnology in treatment of methicillin-resistant Staphylococcus aureus

Y Gao, Y Chen, Y Cao, A Mo, Q Peng - European journal of medicinal …, 2021 - Elsevier
Abuse of antibiotics has led to the emergence of drug-resistant pathogens. Methicillin-
resistant Staphylococcus aureus (MRSA) was reported just two years after the clinical use of …

Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity

D Gerlach, Y Guo, C De Castro, SH Kim, K Schlatterer… - Nature, 2018 - nature.com
Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent cause of difficult-to-treat,
often fatal infections in humans,. Most humans have antibodies against S. aureus, but these …

An Update on Clinical Burden, Diagnostic Tools, and Therapeutic Options of Staphylococcus aureus

PN Reddy, K Srirama… - … Diseases: Research and …, 2017 - journals.sagepub.com
Staphylococcus aureus is an important pathogen responsible for a variety of diseases
ranging from mild skin and soft tissue infections, food poisoning to highly serious diseases …

Wall teichoic acid in Staphylococcus aureus host interaction

R van Dalen, A Peschel, NM van Sorge - Trends in microbiology, 2020 - cell.com
Staphylococcus aureus is a major opportunistic human pathogen that frequently causes
disease in community and hospital settings. Nasal colonization is an important risk factor for …

CRISPR-Cas system as a promising player against bacterial infection and antibiotic resistance

M Abavisani, R Khayami, M Hoseinzadeh… - Drug Resistance …, 2023 - Elsevier
The phenomenon of antibiotic resistance (AR) and its increasing global trends and
destructive waves concerns patients and the healthcare system. In order to combat AR, it is …

Human encroachment into wildlife gut microbiomes

G Fackelmann, MAF Gillingham, J Schmid… - Communications …, 2021 - nature.com
In the Anthropocene, humans, domesticated animals, wildlife, and their environments are
interconnected, especially as humans advance further into wildlife habitats. Wildlife gut …