Stem cell-based treatments have been suggested as promising candidates for stroke.
Recently, mesenchymal stem cells (MSCs) have been reported as potential therapeutics for …

The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …

During the pathogenesis of systemic inflammation, reactive oxygen species (ROS) circulate
in the bloodstream and interact with endothelial cells (ECs), increasing intracellular …

Mesenchymal stem/stromal cells (MSCs) are extensively studied as cell-therapy agents for
neurological diseases. Recent studies consider exosomes secreted by MSCs as important …

Intracerebral hemorrhage (ICH) has high morbidity and mortality, with no effective treatment
at present. One possible therapeutic strategy involves the use of mesenchymal stem cells …

The transient receptor potential melastatin (TRPM) protein family is an extensive group of
ion channels expressed in several types of mammalian cells. Many studies have shown that …

Transient receptor potential (TRP) cation channels represent a large and diverse family of
ion channels that act as important transducers of sensory information. The Melastatin …

Calcium signaling in phagocytes is essential for cellular activation, migration, and the
potential resolution of infection or inflammation. The generation of reactive oxygen species …

As the second most abundant intracellular divalent cation, magnesium (Mg2+) is essential
for cell functions, such as ATP production, protein/DNA synthesis, protein activity, and …

Fibrotic disorders are typically characterised by excessive connective tissue and
extracellular matrix (ECM) deposition that preclude the normal healing of different tissues …