Telomere shortening is a well-known hallmark of both cellular senescence and organismal
aging. An accelerated rate of telomere attrition is also a common feature of age-related …

Objective To assess the association between leucocyte telomere length and risk of
cardiovascular disease. Design Systematic review and meta-analysis. Data sources Studies …

Telomere attrition is associated with increased morbidity and mortality of various age-related
diseases. Reports of association between telomere length (TL) and all-cause mortality …

Telomeres protect the integrity of information-carrying DNA by serving as caps on the
terminal portions of chromosomes. Telomere length decreases with aging, and this …

World population has been continuously increasing and progressively aging. Aging is
characterized by a complex and intraindividual process associated with nine major cellular …

Telomeres are nucleoprotein caps flanking DNA. They are shortened by cell division and
oxidative stress and are lengthened by the enzyme telomerase and DNA exchange during …

The attrition of telomeres, the ends of eukaryote chromosomes, is thought to play an
important role in cell deterioration with advancing age. The observed variation in telomere …

Background—Telomeres are repetitive, gene-poor regions that cap the ends of DNA and
help maintain chromosomal integrity. Their shortening is caused by inflammation and …

Many psychiatric illnesses are associated with early mortality and with an increased risk of
developing physical diseases that are more typically seen in the elderly. Moreover, certain …

OBJECTIVE: To provide a systematic review of the relationship between age and leukocyte
telomere length (LTL) in adults. METHODS: Relevant studies were identified by a systematic …