Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …

Rolling circle amplification (RCA) is an isothermal enzymatic process where a short DNA or
RNA primer is amplified to form a long single stranded DNA or RNA using a circular DNA …

As an emerging sequencing technology, single-cell RNA sequencing (scRNA-Seq) has
become a powerful tool for describing cell subpopulation classification and cell …

DNA analysis is frequently used to acquire information from biological material to aid
enquiries associated with criminal offences, disaster victim identification and missing …

Herbarium collections are potentially an enormous resource for DNA studies, but the use of
herbarium specimens in molecular studies has thus far been slowed down by difficulty in …

BACKGROUND HIV-1 viremia that is not suppressed by combination antiretroviral therapy
(ART) is generally attributed to incomplete medication adherence and/or drug resistance …

Genome sequencing of single cells has a variety of applications, including characterizing
difficult-to-culture microorganisms and identifying somatic mutations in single cells from …

Background Single-cell genome sequencing has the potential to allow the in-depth
exploration of the vast genetic diversity found in uncultured microbes. We used the marine …

Studying complex biological systems such as a developing embryo, a tumor, or a microbial
ecosystem often involves understanding the behavior and heterogeneity of the individual …

All vertically transmitted bacterial symbionts undergo a process of genome reduction over
time, resulting in tiny, gene-dense genomes. Comparison of genomes of ancient bacterial …