Background Scarce data are available on the use of vedolizumab in children with
inflammatory bowel disease (IBD). We aimed to evaluate the safety, effectiveness, and …

Background Thiopurines and methotrexate have long been used to maintain remission in
Crohn's disease [CD]. In this nationwide study, we aimed to compare the effectiveness and …

Introduction Children and adolescents with Crohn's disease present unique challenges due
to extensive disease at diagnosis and the effect of bowel inflammation on growth. Historical …

Background In this nationwide study we aimed to compare the durability of the first initiated
biologic in Crohn's disease [CD], stratified by monotherapy and combotherapy. Methods We …

Background It has been reported that inflammatory bowel disease (IBD) is associated with
an increased risk of malignancies, including lymphoma. A number of large observational …

Objectives: Pediatric-onset inflammatory bowel disease (pIBD) increases the risk of
developing several different cancer forms. In this case-control study, we aimed to assess the …

Background Rare and severe adverse events can occur in children with inflammatory bowel
disease (IBD), and the relationship with disease or drug treatment is often uncertain. We …

METHODS: We analyzed administrative claims from the 2007 to 2018 IQVIA database and
identified pediatric (≤ 18 years) patients with Crohn's disease or ulcerative colitis using …

Methods: We conducted a retrospective review of children (2–18 years) with UC treated with
thiopurines between January 2008 and January 2019 at 7 medical centers in Israel. The …

Introduction Anti-tumor necrosis factor (TNF) antibodies play a major role in treating
inflammatory bowel disease (IBD), both in adult and pediatric patients. While there is a large …