Strategies in Electrospun Polymer and Hybrid Scaffolds for Enhanced Cell Integration and Vascularization for Bone Tissue Engineering and Organoids

M Polak, JE Karbowniczek… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Addressing the demand for bone substitutes, tissue engineering responds to the high
prevalence of orthopedic surgeries worldwide and the limitations of conventional tissue …

[HTML][HTML] A 3D bioreactor model to study osteocyte differentiation and mechanobiology under perfusion and compressive mechanical loading

WD Rindt, M Krug, S Yamada, F Sennefelder, L Belz… - Acta biomaterialia, 2024 - Elsevier
Osteocytes perceive and process mechanical stimuli in the lacuno-canalicular network in
bone. As a result, they secrete signaling molecules that mediate bone formation and …

Finite element analysis of vertebroplasty in the osteoporotic T11‐L1 vertebral body: Effects of bone cement formulation

S Mondal, DB MacManus… - … Research Part B …, 2024 - Wiley Online Library
Vertebral compression fractures are one of the most severe clinical consequences of
osteoporosis and the most common fragility fracture afflicting 570 and 1070 out of 100,000 …

Evaluation of mechanobiological potential of 3D-printed PLA bone tissue scaffolds with different pore architectures and porosity ratios

S Şenaysoy, H Lekesiz - … Journal of 3D Printing Technologies and …, 2024 - dergipark.org.tr
Lattice structures are widely used in bone tissue scaffold designs due to interconnected
porous structures that mimic the natural extracellular matrix (ECM) to treat large bone …

A 3D Bioreactor Model to Study Late Osteocyte Differentiation and Mechanobiology Under Perfusion and Compressive Mechanical Loading

WD Rindt, M Krug, S Yamada, F Sennefelder, L Belz… - papers.ssrn.com
Osteocytes perceive and process mechanical stimuli in bone. As a result, they secrete
signaling molecules that mediate bone formation and resorption. To date, few three …

[PDF][PDF] A mechanically stimulated co-culture in 3D composite scaffolds promotes osteogenic and anti-osteoclastogenic activity and M2 macrophage polarization

GI Kontogianni, K Loukelis, AF Bonatti… - Biomaterials …, 2020 - spj.science.org
Bone is subjected to a plethora of mechanical stresses, which have been found to directly
influence the equilibrium between bone resorption and formation. Taking this into account …