The packaging of DNA into chromatin in eukaryotes regulates gene transcription, DNA
replication and DNA repair. ATP-dependent chromatin remodelling enzymes (re) arrange …

Chromatin remodelers act to regulate multiple cellular processes, such as transcription and
DNA repair, by controlling access to genomic DNA. Four families of chromatin remodelers …

DNA wraps around the histone octamer to form nucleosomes, the repeating unit of
chromatin, which create barriers for accessing genetic information. Snf2-like chromatin …

Background Aberrant changes in epigenetic mechanisms such as histone modifications play
an important role in cancer progression. PRMT1 which triggers asymmetric dimethylation of …

Chromatin-remodelling complexes of the SWI/SNF family function in the formation of
nucleosome-depleted, transcriptionally active promoter regions (NDRs),. In the yeast …

A large family of chromatin remodelers that noncovalently modify chromatin is crucial in cell
development and differentiation. They are often the targets of cancer, neurological disorders …

Chromatin remodeling ATP ases and their associated complexes can alter the accessibility
of the genome in the context of chromatin by using energy derived from the hydrolysis of …

SMARCB1 (INI1/SNF5/BAF47), a core subunit of the SWI/SNF (BAF) chromatin-remodeling
complex, is inactivated in the large majority of rhabdoid tumors, and germline heterozygous …

Mammalian SWI/SNF enzymes are ATP-dependent remodelers of chromatin structure.
These multisubunit enzymes are heterogeneous in composition; there are two catalytic …

Chromatin-remodelling complexes (CRCs) mobilize nucleosomes to mediate the access of
DNA-binding factors to their sites in vivo. These CRCs contain a catalytic subunit that bears …