BACKGROUND The idea that memory is stored as enduring changes in the brain dates
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …

Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Sex differences are reported in hippocampal plasticity, cognition, and in a number of
disorders that target the integrity of the hippocampus. For example, meta-analyses reveal …

Associating multiple sensory cues with objects and experience is a fundamental brain
process that improves object recognition and memory performance. However, neural …

The hippocampus has a pivotal role in learning and in the formation and consolidation of
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …

The last decade has seen dramatic technological and conceptual changes in research on
episodic memory and the brain. New technologies, and increased use of more naturalistic …

Classical Hebbian learning puts the emphasis on joint pre-and postsynaptic activity, but
neglects the potential role of neuromodulators. Since neuromodulators convey information …

The mechanisms for pattern completion and pattern separation are described in the context
of a theory of hippocampal function in which the hippocampal CA3 system operates as a …

Neuronal ensembles are coactive groups of neurons that may represent building blocks of
cortical circuits. These ensembles could be formed by Hebbian plasticity, whereby synapses …

The aims of the paper are to update Rolls' quantitative computational theory of hippocampal
function and the predictions it makes about the different subregions (dentate gyrus, CA3 and …