Dendritic NMDA receptors in parvalbumin neurons enable strong and stable neuronal assemblies

JH Cornford, MS Mercier, M Leite, V Magloire… - Elife, 2019 - elifesciences.org
Parvalbumin-expressing (PV+) GABAergic interneurons mediate feedforward and feedback
inhibition and have a key role in gamma oscillations and information processing. The …

The NeuroML ecosystem for standardized multi-scale modeling in neuroscience

A Sinha, P Gleeson, B Marin, S Dura-Bernal… - Elife, 2025 - elifesciences.org
Data-driven models of neurons and circuits are important for understanding how the
properties of membrane conductances, synapses, dendrites, and the anatomical …

Combining theory, model, and experiment to explain how intrinsic theta rhythms are generated in an in vitro whole hippocampus preparation without oscillatory inputs

KA Ferguson, AP Chatzikalymniou, FK Skinner - eneuro, 2017 - eneuro.org
Scientists have observed local field potential theta rhythms (3–12 Hz) in the hippocampus
for decades, but understanding the mechanisms underlying their generation is complicated …

Network models provide insights into how oriens–lacunosum-moleculare and bistratified cell interactions influence the power of local hippocampal CA1 theta …

KA Ferguson, CYL Huh, B Amilhon… - Frontiers in systems …, 2015 - frontiersin.org
Hippocampal theta is a 4–12 Hz rhythm associated with episodic memory, and although it
has been studied extensively, the cellular mechanisms underlying its generation are …

Examining the limits of cellular adaptation bursting mechanisms in biologically-based excitatory networks of the hippocampus

KA Ferguson, F Njap, W Nicola, FK Skinner… - Journal of …, 2015 - Springer
Determining the biological details and mechanisms that are essential for the generation of
population rhythms in the mammalian brain is a challenging problem. This problem cannot …

A hypothesis for theta rhythm frequency control in CA1 microcircuits

FK Skinner, S Rich, AR Lunyov, J Lefebvre… - Frontiers in neural …, 2021 - frontiersin.org
Computational models of neural circuits with varying levels of biophysical detail have been
generated in pursuit of an underlying mechanism explaining the ubiquitous hippocampal …

CA1 pyramidal cells have diverse biophysical properties, affected by development, experience, and aging

EC McKiernan, DF Marrone - PeerJ, 2017 - peerj.com
Neuron types (eg, pyramidal cells) within one area of the brain are often considered
homogeneous, despite variability in their biophysical properties. Here we review literature …

Data-driven predictive modeling of neuronal dynamics using long short-term memory

B Plaster, G Kumar - Algorithms, 2019 - mdpi.com
Modeling brain dynamics to better understand and control complex behaviors underlying
various cognitive brain functions have been of interest to engineers, mathematicians and …

One-dimensional population density approaches to recurrently coupled networks of neurons with noise

W Nicola, C Ly, SA Campbell - SIAM Journal on Applied Mathematics, 2015 - SIAM
Mean-field systems have been previously derived for networks of coupled, two-dimensional,
integrate-and-fire neurons such as the Izhikevich, adapting exponential, and quartic …

Linking minimal and detailed models of CA1 microcircuits reveals how theta rhythms emerge and their frequencies controlled

AP Chatzikalymniou, M Gumus, FK Skinner - Hippocampus, 2021 - Wiley Online Library
The wide variety of cell types and their biophysical complexities pose a challenge in our
ability to understand oscillatory activities produced by cellular‐based computational network …