Epidemiology of sarcopenia and insight into possible therapeutic targets

EM Dennison, AA Sayer, C Cooper - Nature Reviews Rheumatology, 2017 - nature.com
Musculoskeletal ageing is a major public health concern owing to demographic shifts in the
population. Sarcopenia, generally defined as the age-related loss of muscle mass and …

Epidemiology of sarcopenia: determinants throughout the lifecourse

SC Shaw, EM Dennison, C Cooper - Calcified tissue international, 2017 - Springer
Sarcopenia is an age-related syndrome characterised by progressive and generalised loss
of skeletal muscle mass and strength; it is a major contributor to the risk of physical frailty …

Association between sarcopenia and levels of growth hormone and insulin-like growth factor-1 in the elderly

A Bian, Y Ma, X Zhou, Y Guo, W Wang, Y Zhang… - BMC musculoskeletal …, 2020 - Springer
Background Age-related sarcopenia is a serious global health issue in elderly individuals
and for the community as it induces disability and significant economic burden. The purpose …

Smoking-induced skeletal muscle dysfunction. From evidence to mechanisms

H Degens, G Gayan-Ramirez… - American journal of …, 2015 - atsjournals.org
Smoking is the most important risk factor for the development of chronic obstructive
pulmonary disease (COPD). Patients with COPD commonly suffer from skeletal muscle …

[HTML][HTML] Cigarette smoking and musculoskeletal disorders

M Abate, D Vanni, A Pantalone… - Muscles, ligaments and …, 2013 - ncbi.nlm.nih.gov
Cigarette smoking has deleterious effects on the musculo-skeletal system. The loss of bone
mineral content and increased incidence of fractures are the best known negative …

The effect of tobacco smoking on musculoskeletal health: a systematic review

AM Al-Bashaireh, LG Haddad… - … of environmental and …, 2018 - Wiley Online Library
This systematic review explored associations between smoking and health outcomes
involving the musculoskeletal system. AMSTAR criteria were followed. A comprehensive …

Sarcopenia

N Fuggle, S Shaw, E Dennison, C Cooper - Best Practice & Research …, 2017 - Elsevier
Sarcopenia is a condition that is characterized by loss of muscle mass, muscle strength and
muscle functional impairment with ageing. The definition of sarcopenia has been through …

Nutrition and respiratory health—feature review

BS Berthon, LG Wood - Nutrients, 2015 - mdpi.com
Diet and nutrition may be important modifiable risk factors for the development, progression
and management of obstructive lung diseases such as asthma and chronic obstructive …

Factors associated with grip strength decline in older adults

O Sternäng, CA Reynolds, D Finkel… - Age and …, 2015 - academic.oup.com
Background: few studies have examined associations of multi-faceted demographic, health
and lifestyle factors with long-term change in grip strength performance across the adult …

High CO2 levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific Ring finger protein 1 (MuRF1)

A Jaitovich, M Angulo, E Lecuona, LA Dada… - Journal of Biological …, 2015 - ASBMB
Patients with chronic obstructive pulmonary disease, acute lung injury, and critical care
illness may develop hypercapnia. Many of these patients often have muscle dysfunction …