Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Resilience of neural networks for locomotion

G Haspel, KE Severi, LJ Fauci, N Cohen… - The Journal of …, 2021 - Wiley Online Library
Locomotion is an essential behaviour for the survival of all animals. The neural circuitry
underlying locomotion is therefore highly robust to a wide variety of perturbations, including …

Proprioceptive feedback amplification restores effective locomotion in a neuromechanical model of lampreys with spinal injuries

C Hamlet, L Fauci, JR Morgan… - Proceedings of the …, 2023 - National Acad Sciences
Spinal injuries in many vertebrates can result in partial or complete loss of locomotor ability.
While mammals often experience permanent loss, some nonmammals, such as lampreys …

Mechanosensory feedback in lamprey swimming models and applications in the field of spinal cord regeneration

HR Katz, CL Hamlet - Integrative and Comparative Biology, 2023 - academic.oup.com
The central pattern generator (CPG) in anguilliform swimming has served as a model for
examining the neural basis of locomotion. This system has been particularly valuable for the …

Lampreys and spinal cord regeneration:“a very special claim on the interest of zoologists,” 1830s-present

K Maxson Jones, JR Morgan - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Employing history of science methods, including analyses of the scientific literature, archival
documents, and interviews with scientists, this paper presents a history of lampreys in …

Recovery of burrowing behavior after spinal cord injury in the larval sea lamprey

HR Katz, KE Fouke, NA Losurdo… - The Biological …, 2020 - journals.uchicago.edu
Following traumatic spinal cord injury, most mammalian species are unable to achieve
substantial neuronal regeneration and often experience loss of locomotor function. In …

The functional properties of synapses made by regenerated axons across spinal cord lesion sites in lamprey

D Parker - Neural Regeneration Research, 2022 - journals.lww.com
While the anatomical properties of regenerated axons across spinal cord lesion sites have
been studied extensively, little is known of how the functional properties of regenerated …

Swimming kinematics and performance of spinal transected lampreys with different levels of axon regeneration

J Fies, BJ Gemmell, SM Fogerson… - Journal of …, 2021 - journals.biologists.com
Axon regeneration is critical for restoring neural function after spinal cord injury. This has
prompted a series of studies on the neural and functional recovery of lampreys after spinal …

Data on the quantification of aspartate, GABA and glutamine levels in the spinal cord of larval sea lampreys after a complete spinal cord injury

B Fernández-López, N Pereiro, A Lafuente… - Data, 2021 - mdpi.com
We used high-performance liquid chromatography (HPLC) methods to quantify aspartate,
GABA, and glutamine levels in the spinal cord of larval sea lampreys following a complete …

[引用][C] 七鳃鳗脊髓病变部位再生轴突的生理学功能特性

D Parker - 中国神经再生研究(英文版), 2022