Diabetic nephropathy (DN) is one of the most severe complications of diabetes. However,
due to its complex pathological mechanisms, no effective therapeutic methods (other than …

Over the past decades, aggressive control of blood pressure (BP) and blockade of the renin–
angiotensin–aldosterone system (RAAS) were considered the cornerstones of treatment …

Diabet. Med. 27, 1144–1150 (2010) Abstract Aims Our aim was to evaluate the markers of
tubulointerstitial damage, neutrophil gelatinase‐associated lipocalin (NGAL) and kidney …

Management of hypertension and albuminuria are considered among the primary goals of
treatment to slow the progression of chronic kidney disease (CKD). Renin-angiotensin …

Hypothesis/objectives: Early prevention of diabetic nephropathy by way of blocking the renin-
angiotensin system (RAS) in patients with normoalbuminuria seems rational, but trials have …

OBJECTIVE We studied tubular and glomerular damage in type 1 diabetic patients by
measuring urinary–liver fatty acid binding protein (U-LFABP) and albuminuria …

Hyperglycemia, increased inflammation, and mitochondrial dysfunction in diabetes may
eventually cause kidney damage. Black rice cyanidin-3-glucoside has anti-hyperglycemic …

The renin–angiotensin–aldosterone system (RAAS), an important regulator of blood
pressure as well as fluid and electrolyte balance, plays an important role in the …

An incomplete inhibition of the renin angiotensin aldosterone system (RAAS) may be
responsible for the residual organ damage and event rate that still occur in spite of an …

Aim The optimal antiproteinuric dose of aliskiren is unknown. This study compared the effect
of placebo and increasing doses of aliskiren on urinary albumin excretion rate (UAER) …