Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With Onchocerca ochengi

B Zhan, ME Bottazzi, PJ Hotez… - Frontiers in Cellular and …, 2022 - frontiersin.org
Human onchocerciasis is a devastating neglected tropical disease caused by infection of the
filarial nematode Onchocerca volvulus. The infection can cause irreversible visual …

[HTML][HTML] Human IgE mAbs identify major antigens of parasitic worm infection

A Hadadianpour, J Daniel, J Zhang, BW Spiller… - Journal of Allergy and …, 2022 - Elsevier
Background Much of our understanding of the targets of IgE comes from studies of allergy,
though little is known about the natural immunogenic targets seen after parasitic worm …

Clinical utility of microarray B‐cell epitope mapping in food allergies: A systematic review

L Sánchez‐Ruano, B de la Hoz… - Pediatric Allergy and …, 2020 - Wiley Online Library
Background Peptide microarray technology has been proposed as a useful tool for
diagnosing food allergy. However, there is considerable heterogeneity in the clinical …

Protein biomarker discovery and fast monitoring for the identification and detection of Anisakids by parallel reaction monitoring (PRM) mass spectrometry

M Carrera, JM Gallardo, S Pascual, ÁF González… - Journal of …, 2016 - Elsevier
Anisakids are fish-borne parasites that are responsible for a large number of human
infections and allergic reactions around the world. World health organizations and food …

Previous exposure to the fish parasite Anisakis as a potential risk factor for gastric or colon adenocarcinoma

JC Garcia-Perez, R Rodríguez-Perez, A Ballestero… - Medicine, 2015 - journals.lww.com
Anisakiasis is a global disease caused by consumption of raw or lightly cooked fish
contaminated with L3 Anisakis spp. larvae. High rates of parasitization of fish worldwide …

Mass Spectrometry Based-Proteomic Analysis of Anisakis spp.: A Preliminary Study towards a New Diagnostic Tool

V Marzano, S Pane, G Foglietta, S Levi Mortera… - Genes, 2020 - mdpi.com
Anisakiasis is nowadays a well-known infection, mainly caused by the accidental ingestion
of Anisakis larvae, following the consumption of raw or undercooked fishes and …

A magnesium-induced triplex pre-organizes the SAM-II riboswitch

S Roy, H Lammert, RL Hayes, B Chen… - PLoS computational …, 2017 - journals.plos.org
Our 13C-and 1H-chemical exchange saturation transfer (CEST) experiments previously
revealed a dynamic exchange between partially closed and open conformations of the SAM …

Identification and Physicochemical Characterization of a New Allergen from Ascaris lumbricoides

V Ahumada, M Manotas, J Zakzuk, L Aglas… - International journal of …, 2020 - mdpi.com
To analyze the impact of Ascaris lumbricoides infection on the pathogenesis and diagnosis
of allergic diseases, new allergens should be identified. We report the identification of a new …

Exploring tumourigenic potential of the parasite Anisakis: a pilot study

MT Corcuera, C Rodríguez-Bobada, J Zuloaga… - Parasitology …, 2018 - Springer
Anisakiasis is a global disease caused by consumption of raw or lightly cooked fish
parasitised with Anisakis spp. third-stage larvae. Cases in the literature show colocalised …

Proteomic and Bioinformatic Investigations of Heat-Treated Anisakis simplex Third-Stage Larvae

M Kochanowski, M Różycki, J Dąbrowska, A Bełcik… - Biomolecules, 2020 - mdpi.com
Anisakis simplex third-stage larvae are the main source of hidden allergens in marine fish
products. Some Anisakis allergens are thermostable and, even highly processed, could …