Functional recovery from peripheral nerve injury and repair depends on a multitude of
factors, both intrinsic and extrinsic to neurons. Neuronal survival after axotomy is a …

The neurotrophins are growth factors that play critical roles in the development,
maintenance, survival, and death of the nervous system. The signal transducing systems …

The role of neurotrophic factors in the maintenance and survival of peripheral neuronal cells
has been the subject of numerous studies. Administration of exogenous neurotrophic factors …

Cadherins are Ca2+-dependent cell-cell adhesion molecules that play critical roles in
animal morphogenesis. Various cadherin-related molecules have also been identified …

Peripheral nerve regeneration comprises the formation of axonal sprouts, their outgrowth as
regenerating axons and the reinnervation of original targets. This review focuses on the …

The lack of axonal regeneration in the injured adult mammalian spinal cord leads to
permanent functional impairment. To induce axonal regeneration in the transected adult rat …

We investigate the signaling mechanisms that induce retinal ganglion cell (RGC) axon
elongation by asking whether surviving neurons extend axons by default. We show that bcl …

Terminal Schwann cells overlying the neuromuscular junction sprout elaborate processes
upon muscle denervation. We show here that motor axons use these processes as …

The failure of regenerating axons to grow within the adult mammalian central nervous
system (CNS) does not apply to the olfactory bulb (OB). In this structure, normal and …

The development of neurons and virtually all other cell types in the organism depends upon
interactions with molecules in their environment. Studics of individual cell types have …