Synthetic glucocorticoids are widely used for their anti-inflammatory and
immunosuppressive actions. A possible unwanted effect of glucocorticoid treatment is …

Corticosteroids remain the mainstay of the treatment for various ocular conditions affecting
the ocular surface, anterior and posterior segments of the eye due to their anti-inflammatory …

Asthma and chronic obstructive pulmonary disease (COPD) are obstructive airway disorders
which differ in their underlying causes and phenotypes but overlap in patterns of …

Hypoxia and inflammation have been associated with a number of pathological conditions,
in particular inflammatory diseases. While hypoxia is mainly associated with the activation of …

Glucocorticosteroids are a group of structurally related molecules that includes natural
hormones and synthetic drugs with a wide range of anti‐inflammatory potencies. For …

Rationale: Radiographically confirmed pneumonia risk with inhaled corticosteroid use in
chronic obstructive pulmonary disease (COPD) has not been assessed to date. Objectives …

Glucocorticoids are widely used to treat various inflammatory lung diseases. Acting via the
glucocorticoid receptor (GR), they exert clinical effects predominantly by modulating gene …

Background Combination therapy with an inhaled corticosteroid (ICS) and long-acting β2
agonist (LABA) is recommended for patients with asthma symptomatic on ICS alone …

Highlights•Inhaled medicines are cornerstones in the treatment of asthma/COPD
today.•Significant unmet medical need remains in the treatment of respiratory diseases.•The …

Background: Fluticasone furoate is a new enhanced‐affinity glucocorticoid with a unique
combination of pharmacodynamic and physicochemical properties suitable for topical …