Background Gastric cancer (GC) is one of the most common cancers in Iran. Knowledge of
the epidemiology of the disease is essential in planning for prevention. So this study aimed …

Cancer cells can evade immune elimination by activating immunosuppressive signaling
pathways in the tumor microenvironment (TME). Targeting immunosuppressive signaling …

Background There is a declining trend of gastric cancer (GC) incidence in the world during
recent years that is related to the development of novel diagnostic methods. However, there …

Single nucleotide polymorphisms (SNPs) of the IL-16 gene have been reported to influence
the risk of several cancers, but their role in ovarian cancer (OC) has not been studied. Using …

Background/Aim: Elevated serum interleukin-16 (IL-16) levels have been reported in gastric
cancer (GC) tissues; however, the role of IL-16 genotypes in GC susceptibility remains …

Tristetraprolin (TTP) is an adenine/uridine (AU)-rich element (ARE)-binding protein that can
induce degradation of mRNAs. In this study, we report that TTP suppresses the expression …

Cancer-associated fibroblasts (CAFs) are key components in tumor microenvironment
(TME). The secreted products of CAFs play important roles in regulating tumor cells and …

Background Surgery is the standard treatment for early-stage NSCLC, and platinum-based
chemotherapy remains as the treatment of choice for advanced-stage NSCLC patients with …

Interleukin (IL) 16 plays a key role in inflammatory diseases as well as in tumorigenesis of
osteosarcoma (OS). The aim of this study was to investigate the association of IL16 …

Summary Interleukin‐16 (IL‐16) is a multifunctional pro‐inflammatory cytokine that was
previously found in association with complex disorders, and it is now cleared that this …