Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …

Many important interactions between bacterial pathogens and their hosts are highly specific
binding events that involve host or pathogen carbohydrate structures (glycans). Glycan …

Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

O-glycosylation is a highly frequent post-translation modification of proteins, with important
functional implications in both physiological and disease contexts. The biosynthesis of O …

ABSTRACT A close symbiotic relationship exists between the intestinal microbiota and its
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …

All mucins are highly O-glycosylated by variable glycans depending on species, histoblood
group and organ. This makes the intestinal main mucin MUC2 non-degradable by the host …

The complex multi-step process of glycosylation occurs in a single cell, yet current analytics
generally cannot measure the output (the glycome) of a single cell. Here, we addressed this …

Vaccination is one of the greatest achievements in biomedical research preventing death
and morbidity in many infectious diseases through the induction of pathogen‐specific …

Helicobacter species infections may be associated with the development of gastric
disorders, such as gastritis, peptic ulcers, intestinal metaplasia, dysplasia and gastric …