Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …

CYP1A1 is one of the main cytochrome P450 enzymes, examined extensively for its capacity
to activate compounds with carcinogenic properties. Continuous exposure to inhalation …

The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …

A series of new 2-phenylbenzothiazoles has been synthesized on the basis of the discovery
of the potent and selective in vitro antitumor properties of 2-(3, 4-dimethoxyphenyl)-5 …

A novel and practical fluoroalkyl radical-initiated cascade reaction was developed to access
diverse 2-fluoroalkylbenzothiazoles by reacting various fluoroalkyl radical sources, including …

New fluorinated 2-aryl-benzothiazoles,-benzoxazoles, and-chromen-4-ones have been
synthesized and their activity against MCF-7 and MDA 468 breast cancer cell lines …

A new series of bis-benzimidazole clubbed with primary amine (3i-iii) and aromatic
aldehydes (4i-ix) were design and synthesize with an intention to search an anticancer lead …

Benzothiazoles have played an important role in the field of biochemistry and medicinal
chemistry due to their highly pharmaceutical and biological activity. The development of …

Cytochrome P450s (CYPs) represent a large class of heme-containing enzymes that
catalyze the metabolism of multitudes of substrates both endogenous and exogenous. Until …

Background: Because cancer is a complex disease, it is unlikely that a single mono
functional 'targeted'drug will be effective for treating this most advanced disease. Combined …