Pathophysiology and treatment of stroke: present status and future perspectives

D Kuriakose, Z Xiao - International journal of molecular sciences, 2020 - mdpi.com
Stroke is the second leading cause of death and a major contributor to disability worldwide.
The prevalence of stroke is highest in developing countries, with ischemic stroke being the …

Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a …

WJ Powers, AA Rabinstein, T Ackerson, OM Adeoye… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations in a single document for clinicians caring for adult …

Thrombolysis for acute ischaemic stroke: current status and future perspectives

G Tsivgoulis, AH Katsanos, EC Sandset, G Turc… - The Lancet …, 2023 - thelancet.com
Alteplase is currently the only approved thrombolytic agent for treatment of acute ischaemic
stroke, but interest is burgeoning in the development of new thrombolytic agents for systemic …

Thrombectomy for distal, medium vessel occlusions: a consensus statement on present knowledge and promising directions

JL Saver, R Chapot, R Agid, AE Hassan, AP Jadhav… - Stroke, 2020 - Am Heart Assoc
Endovascular thrombectomy (EVT) is well established as a highly effective treatment for
acute ischemic stroke (AIS) due to proximal, large vessel occlusions (PLVOs). With iterative …

2018 guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association …

WJ Powers, AA Rabinstein, T Ackerson, OM Adeoye… - stroke, 2018 - Am Heart Assoc
2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A
Guideline for Healthcare Professionals From the American Heart Association/American Stroke …

Multisociety consensus quality improvement revised consensus statement for endovascular therapy of acute ischemic stroke

D Sacks, B Baxter, BCV Campbell… - … journal of stroke, 2018 - journals.sagepub.com
Endovascular therapy (EVT) for acute ischemic stroke in selected patients has recently been
proven effective in several clinical trials, and the widespread adoption of thrombectomy into …

Evolution of the modified Rankin scale and its use in future stroke trials

JP Broderick, O Adeoye, J Elm - Stroke, 2017 - Am Heart Assoc
2008 Stroke July 2017 mRS that depend, in part, on meeting or not meeting the proportional
odds assumption. 16, 18 After scientific discussion and debate in the field, investigators …

Indications for mechanical thrombectomy for acute ischemic stroke: current guidelines and beyond

AP Jadhav, SM Desai, TG Jovin - Neurology, 2021 - AAN Enterprises
Purpose of the Review This article reviews recent breakthroughs in the treatment of acute
ischemic stroke, mainly focusing on the evolution of endovascular thrombectomy, its impact …

Randomized assessment of rapid endovascular treatment of ischemic stroke

M Goyal, AM Demchuk, BK Menon… - … England Journal of …, 2015 - Mass Medical Soc
Background Among patients with a proximal vessel occlusion in the anterior circulation, 60
to 80% of patients die within 90 days after stroke onset or do not regain functional …

A randomized trial of intraarterial treatment for acute ischemic stroke

OA Berkhemer, PSS Fransen, D Beumer… - … England Journal of …, 2015 - Mass Medical Soc
Background In patients with acute ischemic stroke caused by a proximal intracranial arterial
occlusion, intraarterial treatment is highly effective for emergency revascularization …