Current oral and non-oral routes of antiepileptic drug delivery

GD Anderson, RP Saneto - Advanced drug delivery reviews, 2012 - Elsevier
Antiepileptic drugs are commonly given orally for chronic treatment of epilepsy. The
treatment of epilepsy requires administration of medications for both acute and chronic …

[HTML][HTML] Intranasal sedatives in pediatric dentistry

MA AlSarheed - Saudi medical journal, 2016 - ncbi.nlm.nih.gov
Objectives: To identify the intranasal (IN) sedatives used to achieve conscious sedation
during dental procedures amongst children. Methods: A literature review was conducted by …

Comparison of drops versus spray administration of intranasal midazolam in two-and three-year-old children for dental sedation

RE Primosch, M Guelmann - Pediatric dentistry, 2005 - ingentaconnect.com
Purpose: The purpose of this retrospective record review of 2-and 3-year-old dental patients
receiving intranasal midazolam (INM) was to compare drops vs spray administration to …

[HTML][HTML] Comparison of oral and buccal midazolam for pediatric dental sedation: a randomized, cross-over, clinical trial for efficacy, acceptance and safety

S Tavassoli-Hojjati, M Mehran, R Haghgoo… - Iranian Journal of …, 2014 - ncbi.nlm.nih.gov
Objective Providing a safe and efficient dental treatment for a young patient is a challenge
for the dentist and the child. The purpose of this study was to investigate the effectiveness …

Anticipatory anxiety in moderately to highly-anxious oral surgery patients as a screening model for anxiolytics: evaluation of alprazolam

DL Wolf, PJ Desjardins, PM Black… - Journal of clinical …, 2003 - journals.lww.com
Alprazolam, a benzodiazepine anxiolytic, was evaluated in anxious patients prior to oral
surgery. This population represents a possible acute screening model for novel anxiolytic …

Comparison of drug acceptance and anxiety between intranasal and sublingual midazolam sedation

AK Shanmugaavel, S Asokan, J John… - Pediatric …, 2016 - ingentaconnect.com
Purpose: The purpose of the study was to assess and compare the changes in anxiety level
and drug acceptance after intranasal and sublingual midazolam sedation. Methods: Forty …

Benzodiazepines used in the treatment of epilepsy

E Trinka, F Brigo - The treatment of epilepsy, 2015 - Wiley Online Library
Benzodiazepines have been used in the treatment of epilepsy since the early 1970s. The
use of benzodiazepines in chronic epilepsy treatment has been limited by concerns for …

Allergic reaction to intranasal midazolam HCl: a case report

M Mcilwain, R Primosch, E Bimstein - Pediatric Dentistry, 2004 - ingentaconnect.com
An acute allergic reaction in a 5-year-old healthy male, after receiving midazolam by
intranasal atomizer for sedation purposes in the dental clinic, was reported. Shortly after the …

Comparative analysis of intravenous midazolam with nasal spray for conscious sedation in minor oral and maxillofacial surgeries

R Kunusoth, G Tej, KKR Ealla… - Journal of Pharmacy …, 2019 - journals.lww.com
Aim: The aim of the current study was to evaluate the efficacy of nasal spray midazolam by
collating it with conventional intravenous midazolam for conscious sedation in minor oral …

Oral health of patients with special needs requiring treatment under general anaesthesia

MAWT Lim, GL Borromeo - Journal of Intellectual & Developmental …, 2019 - Taylor & Francis
Background: General anaesthesia (GA) remains a vital modality to facilitate dental treatment
for patients with special needs but there is limited literature to describe the types of patients …