Understanding food properties is paramount for enhancing features such as appearance,
taste and texture, for improving health-related factors such as minimizing the onset of …

Nucleic acids are central to the storage and transmission of genetic information. Mechanical
properties, along with their sequence, both enable and fundamentally constrain the …

Transmembrane channels and pores have key roles in fundamental biological processes
and in biotechnological applications such as DNA nanopore sequencing,–, resulting in …

We systematically parameterized a coarse-grained (CG) model for DNA that is compatible
with the Martini force field. The model maps each nucleotide into six to seven CG beads and …

We introduce an extended version of oxDNA, a coarse-grained model of deoxyribonucleic
acid (DNA) designed to capture the thermodynamic, structural, and mechanical properties of …

Molecular dynamics simulations play an increasingly important role in the rational design of
(nano)-materials and in the study of biomacromolecules. However, generating input files …

Reproducing the exquisite ion selectivity displayed by biological ion channels in artificial
nanopore systems has proven to be one of the most challenging tasks undertaken by the …

We detect short oligonucleotides and distinguish between sequences that differ by a single
base, using label-free, electronic field-effect transistors (FETs). Our sensing platform utilizes …

Phase separation of intracellular components has been recently realized as a mechanism
by which cells achieve membraneless organization. Here, we study the associative liquid …

Fluorescent base analogs (FBAs) are powerful probes of nucleic acids' structures and
dynamics. However, previously reported FBAs exhibit relatively low brightness and therefore …