Vertebrate CpG islands (CGIs) are short interspersed DNA sequences that deviate
significantly from the average genomic pattern by being GC-rich, CpG-rich, and …

The character of a cell is defined by its constituent proteins, which are the result of specific
patterns of gene expression. Crucial determinants of gene expression patterns are DNA …

Gastric cancer is a major cause of global cancer mortality. We surveyed the spectrum of
somatic alterations in gastric cancer by sequencing the exomes of 15 gastric …

Mammalian genomes are punctuated by DNA sequences containing an atypically high
frequency of CpG sites termed CpG islands (CGIs). CGIs generally lack DNA methylation …

CpG islands (CGIs) are vertebrate genomic landmarks that encompass the promoters of
most genes and often lack DNA methylation. Querying their apparent importance, the …

Living things are unimaginably complex, yet they have withstood a withering assault of
harmful influences over several billion years. These influences include cataclysmic changes …

Mammalian promoters belong to two different categories in terms of base composition and
DNA methylation. In humans and mice, approximately 60% of all promoters colocalize with …

The Fragile X Syndrome (FXS) is one of the most common forms of inherited intellectual
disability in all human societies. Caused by the transcriptional silencing of a single gene, the …

Results: CpGProD is an application for identifying mammalian promoter regions associated
with CpG islands in large genomic sequences. Although it is strictly dedicated to this …

The majority of mammalian gene promoters are encompassed within regions of the genome
called CpG islands that have an elevated level of non-methylated CpG dinucleotides …