New insight into mechanisms of cardiovascular diseases: an integrative analysis approach to identify theranoMiRNAs

F Sessa, M Salerno, M Esposito, G Cocimano… - International Journal of …, 2023 - mdpi.com
MiRNAs regulate both physiological and pathological heart functions. Altered expression of
miRNAs is associated with cardiovascular diseases (CVDs), making miRNAs attractive …

Exploration of the key genes involved in non-alcoholic fatty liver disease and possible microRNA therapeutic targets

A Mahmoudi, A Jalili, AE Butler… - Journal of Clinical and …, 2024 - Elsevier
Background MicroRNAs (miRNAs) are promising therapeutic agents for non-alcoholic fatty
liver disease (NAFLD). This study aimed to identify key genes/proteins involved in NAFLD …

Analysis of the therapeutic potential of miR-124 and miR-16 in non-alcoholic fatty liver disease

A Mahmoudi, A Jalili, SH Aghaee-Bakhtiari… - Journal of Diabetes and …, 2024 - Elsevier
Backgrounds Non-alcoholic fatty liver disease (NAFLD) is a common condition affecting>
25% of the population worldwide. This disorder ranges in severity from simple steatosis (fat …

[HTML][HTML] Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation

S Rezaei, MHJN Abadi, MJ Bazyari, A Jalili… - Iranian Journal of …, 2024 - ncbi.nlm.nih.gov
Objective (s): MicroRNAs, which are micro-coordinators of gene expression, have been
recently investigated as a potential treatment for cancer. The study used computational …

MiR-16 is promising to be a therapy target to alleviate atherosclerosis

F Yao, Z Shi - Diagnostics and Therapeutics, 2023 - ojs.luminescience.cn
Atherosclerosis is characterized by formation of plaque containing cholesterol and fat-like
substances in the intima of large and middle arteries, which is mostly caused by lipid …

Identification of novel prognostic targets in coronary artery disease and related complications using bioinformatics and next generation sequencing data analysis

B Vastrad, C Vastrad - bioRxiv, 2023 - biorxiv.org
Coronary artery disease (CAD) is the most common cardiovascular disorder and the leading
cause of heart-related deaths in world. Increasing molecular targets have been discovered …