Artificial cells: past, present and future

W Jiang, Z Wu, Z Gao, M Wan, M Zhou, C Mao… - ACS nano, 2022 - ACS Publications
Artificial cells are constructed to imitate natural cells and allow researchers to explore
biological process and the origin of life. The construction methods for artificial cells, through …

Synthetic cells: from simple bio‐inspired modules to sophisticated integrated systems

C Guindani, LC da Silva, S Cao, T Ivanov… - Angewandte …, 2022 - Wiley Online Library
Bottom‐up synthetic biology is the science of building systems that mimic the structure and
function of living cells from scratch. To do this, researchers combine tools from chemistry …

Superstructural ordering in self-sorting coacervate-based protocell networks

W Mu, L Jia, M Zhou, J Wu, Y Lin, S Mann, Y Qiao - Nature Chemistry, 2024 - nature.com
Bottom-up assembly of higher-order cytomimetic systems capable of coordinated physical
behaviours, collective chemical signalling and spatially integrated processing is a key …

Living material assembly of bacteriogenic protocells

C Xu, N Martin, M Li, S Mann - Nature, 2022 - nature.com
Advancing the spontaneous bottom-up construction of artificial cells with high organizational
complexity and diverse functionality remains an unresolved issue at the interface between …

Endocytosis of coacervates into liposomes

T Lu, S Liese, L Schoenmakers, CA Weber… - Journal of the …, 2022 - ACS Publications
Recent studies have shown that the interactions between condensates and biological
membranes are of functional importance. Here, we study how the interaction between …

Plant cell-inspired membranization of coacervate protocells with a structured polysaccharide layer

Y Ji, Y Lin, Y Qiao - Journal of the American Chemical Society, 2023 - ACS Publications
The design of compartmentalized colloids that exhibit biomimetic properties is providing
model systems for developing synthetic cell-like entities (protocells). Inspired by the cell …

Chemical communication at the synthetic cell/living cell interface

V Mukwaya, S Mann, H Dou - Communications Chemistry, 2021 - nature.com
Although the complexity of synthetic cells has continued to increase in recent years,
chemical communication between protocell models and living organisms remains a key …

Peptide‐based coacervate‐core vesicles with semipermeable membranes

M Abbas, JO Law, SN Grellscheid… - Advanced …, 2022 - Wiley Online Library
Coacervates droplets have long been considered as potential protocells to mimic living
cells. However, these droplets lack a membrane and are prone to coalescence, limiting their …

Core-shell microparticles: From rational engineering to diverse applications

X Zhang, Q Qu, A Zhou, Y Wang, J Zhang… - Advances in Colloid and …, 2022 - Elsevier
Core-shell microparticles, composed of solid, liquid, or gas bubbles surrounded by a
protective shell, are gaining considerable attention as intelligent and versatile carriers that …

Coacervate droplets for synthetic cells

Z Lin, T Beneyton, JC Baret, N Martin - Small Methods, 2023 - Wiley Online Library
The design and construction of synthetic cells–human‐made microcompartments that mimic
features of living cells–have experienced a real boom in the past decade. While many efforts …