Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

During division, eukaryotic cells undergo a dramatic, complex and coordinated remodelling
of their cytoskeleton and membranes. For cell division to occur, chromosomes must be …

As the first rate-limiting enzyme in fatty acid oxidation (FAO), CPT1 plays a significant role in
metabolic adaptation in cancer pathogenesis. FAO provides an alternative energy supply for …

Exposure to copper (Cu) has been associated with metabolic disorders in animals and
humans, but the underlying mechanism remains unclear. One-day-old broiler chickens …

Background & Aims Hepatocyte growth and proliferation depends on membrane
phospholipid biosynthesis. Short-chain fatty acids (SCFAs) generated by bacterial …

Lipid membranes are found in most intracellular organelles, and their heterogeneities play
an essential role in regulating the organelles' biochemical functionalities. Here we report a …

The cellular lipidome comprises thousands of unique lipid species. Here, using mass
spectrometry-based targeted lipidomics, we characterize the lipid landscape of human and …

Measuring forces within living cells remains a technical challenge. In this Tutorial, we cover
the development of hydrophobic mechanosensing fluorescent probes called Flippers …

A large body of research has demonstrated that human stearoyl-CoA desaturase 1 (SCD1),
a universally expressed fatty acid Δ9-desaturase that converts saturated fatty acids (SFA) …

Technological innovations have transformed the way scientists approach biological and
clinical questions, transiting from conventional ensemble assays in bulk to emphasize on the …