Cellular redox homeostasis is precisely balanced by generation and elimination of reactive
oxygen species (ROS). ROS are not only capable of causing oxidation of proteins, lipids and …

For a long time, apoptosis was considered the sole form of programmed cell death during
development, homeostasis and disease, whereas necrosis was regarded as an unregulated …

The human heat shock protein 70 (Hsp70) family contains at least eight homologous
chaperone proteins. Endoplasmatic reticulum and mitochondria have their specific Hsp70 …

Abstract Heat shock protein 70 (Hsp70) is an evolutionarily highly conserved molecular
chaperone that promotes the survival of stressed cells by inhibiting lysosomal membrane …

Programmed cell death is essential for the development and maintenance of the immune
system and its responses to exogenous and endogenous stimuli. Studies have …

Lysosomal membrane permeabilization (LMP) occurs in response to a large variety of cell
death stimuli causing release of cathepsins from the lysosomal lumen into the cytosol where …

Terahertz (THz) imaging and sensing technologies are increasingly being used in a host of
medical, military, and security applications. For example, THz systems are now being tested …

Lysosomes, with their arsenal of degradative enzymes are increasingly becoming an area of
interest in the field of oncology. The changes induced in this compartment upon …

The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of
endogenous and exogenous origin. Oxidative stress affects all structures of the human eye …

It is well known that apoptosis is an actively mediated cell suicide process. In contrast,
necrosis, a morphologically distinct form of cell death, has traditionally been regarded as …