The diversification of methods for studying cell–cell interactions and communication
No cell lives in a vacuum, and the molecular interactions between cells define most
phenotypes. Transcriptomics provides rich information to infer cell–cell interactions and …
phenotypes. Transcriptomics provides rich information to infer cell–cell interactions and …
Cell–cell communication inference and analysis in the tumour microenvironments from single-cell transcriptomics: data resources and computational strategies
Carcinomas are complex ecosystems composed of cancer, stromal and immune cells.
Communication between these cells and their microenvironments induces cancer …
Communication between these cells and their microenvironments induces cancer …
Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data
The growing availability of single-cell data, especially transcriptomics, has sparked an
increased interest in the inference of cell-cell communication. Many computational tools …
increased interest in the inference of cell-cell communication. Many computational tools …
Human blastoids model blastocyst development and implantation
One week after fertilization, human embryos implant into the uterus. This event requires the
embryo to form a blastocyst consisting of a sphere encircling a cavity lodging the embryo …
embryo to form a blastocyst consisting of a sphere encircling a cavity lodging the embryo …
CellCall: integrating paired ligand–receptor and transcription factor activities for cell–cell communication
With the dramatic development of single-cell RNA sequencing (scRNA-seq) technologies,
the systematic decoding of cell-cell communication has received great research interest. To …
the systematic decoding of cell-cell communication has received great research interest. To …
Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasis
K Xu, R Wang, H Xie, L Hu, C Wang, J Xu, C Zhu, Y Liu… - Oncogenesis, 2021 - nature.com
Molecular mechanisms underlying breast cancer lymph node metastasis remain unclear.
Using single-cell sequencing, we investigated the transcriptome profile of 96,796 single …
Using single-cell sequencing, we investigated the transcriptome profile of 96,796 single …
A first computational frame for recognizing heparin-binding protein
W Zhu, SS Yuan, J Li, CB Huang, H Lin, B Liao - Diagnostics, 2023 - mdpi.com
Heparin-binding protein (HBP) is a cationic antibacterial protein derived from multinuclear
neutrophils and an important biomarker of infectious diseases. The correct identification of …
neutrophils and an important biomarker of infectious diseases. The correct identification of …
Proteomic dissection of large extracellular vesicle surfaceome unravels interactive surface platform
The extracellular vesicle (EV) surface proteome (surfaceome) acts as a fundamental
signalling gateway by bridging intra‐and extracellular signalling networks, dictates EVs' …
signalling gateway by bridging intra‐and extracellular signalling networks, dictates EVs' …
MetaboliteCOVID: A manually curated database of metabolite markers for COVID-19
L Ren, L Ning, Y Yang, T Yang, X Li, S Tan, P Ge… - Computers in Biology …, 2023 - Elsevier
In the realm of unraveling COVID-19's intricacies, numerous metabolomic investigations
have been conducted to discern the unique metabolic traits exhibited within infected …
have been conducted to discern the unique metabolic traits exhibited within infected …
LIANA+ provides an all-in-one framework for cell–cell communication inference
The growing availability of single-cell and spatially resolved transcriptomics has led to the
development of many approaches to infer cell–cell communication, each capturing only a …
development of many approaches to infer cell–cell communication, each capturing only a …