Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Cell-penetrating peptides in diagnosis and treatment of human diseases: from preclinical research to clinical application

J Xie, Y Bi, H Zhang, S Dong, L Teng, RJ Lee… - Frontiers in …, 2020 - frontiersin.org
Cell-penetrating peptides (CPPs) are short peptides (fewer than 30 amino acids) that have
been predominantly used in basic and preclinical research during the last 30 years. Since …

Combination of cell-penetrating peptides with nanoparticles for therapeutic application: a review

S Silva, AJ Almeida, N Vale - Biomolecules, 2019 - mdpi.com
Cell-penetrating peptides (CPPs), also known as protein translocation domains, membrane
translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid …

Nanoparticles modified with cell-penetrating peptides: Conjugation mechanisms, physicochemical properties, and application in cancer diagnosis and therapy

I Gessner, I Neundorf - International journal of molecular sciences, 2020 - mdpi.com
Based on their tunable physicochemical properties and the possibility of producing cell-
specific platforms through surface modification with functional biomolecules, nanoparticles …

Cell-penetrating peptide: a means of breaking through the physiological barriers of different tissues and organs

J Xu, AR Khan, M Fu, R Wang, J Ji, G Zhai - Journal of Controlled Release, 2019 - Elsevier
The selective infiltration of cell membranes and tissue barriers often blocks the entry of most
active molecules. This natural defense mechanism prevents the invasion of exogenous …

Lipid-Based Nanoparticle Functionalization with Coiled-Coil Peptides for In Vitro and In Vivo Drug Delivery

D Aschmann, RA Knol, A Kros - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus For the delivery of drugs, different nanosized drug carriers (eg, liposomes, lipid
nanoparticles, and micelles) have been developed in order to treat diseases that afflict …

[HTML][HTML] Multifunctional building elements for the construction of peptide drug conjugates

L Xu, S Xu, T Xiang, H Liu, L Chen, B Jiang… - Engineered …, 2022 - Elsevier
Engineering of smart building molecules is key basis in designing intelligent drug delivery
systems. As an emerging sophisticated delivery system strategy, the powerful functions of …

[图书][B] CPP, cell-penetrating peptides

Ü Langel - 2019 - Springer
The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …

Peptides to overcome the limitations of current anticancer and antimicrobial nanotherapies

V Del Genio, R Bellavita, A Falanga, K Hervé-Aubert… - Pharmaceutics, 2022 - mdpi.com
Biomedical research devotes a huge effort to the development of efficient non-viral
nanovectors (NV) to improve the effectiveness of standard therapies. NVs should be stable …

Cellular uptake pathways of nanoparticles: process of endocytosis and factors affecting their fate

S Varma, S Dey, D Palanisamy - Current Pharmaceutical …, 2022 - ingentaconnect.com
Background: Efficient and controlled internalization of NPs into the cells depends on their
physicochemical properties and dynamics of the plasma membrane. NPs-cell interaction is a …