Emergence of Genomic Diversity in the Spike Protein of the “Omicron” Variant

S Basak, P Kayet, M Ghosh, J Chatterjee, S Dutta - Viruses, 2023 - mdpi.com
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus) has constantly been
evolving into different forms throughout its spread in the population. Emerging SARS-CoV-2 …

Natural selection shaped the evolution of amino acid usage in mammalian toll like receptor genes

M Ghosh, S Basak, S Dutta - Computational Biology and Chemistry, 2022 - Elsevier
Toll-like receptors (TLRs) are important as they are able to sense diverse set of pathogens
associated molecular patterns (PAMPs) as ligands. These receptors are involved in …

Automated extraction of information from texts of scientific publications: insights Into HIV treatment strategies

N Biziukova, O Tarasova, S Ivanov, V Poroikov - Frontiers in genetics, 2020 - frontiersin.org
Text analysis can help to identify named entities (NEs) of small molecules, proteins, and
genes. Such data are very important for the analysis of molecular mechanisms of disease …

On the correct interpretation of similarity index in codon usage studies: Comparison with four other metrics and implications for Zika and West Nile virus

A Silverj, O Rota-Stabelli - Virus research, 2020 - Elsevier
Viruses can modify the usage of their synonymous codons to mimic that of their hosts:
investigation of codon usage may therefore help increase our understanding of virus …

HIV long-term non-progressors share similar features with simian immunodeficiency virus infection of chimpanzees

A Roy, S Basak - Journal of Biomolecular Structure and Dynamics, 2021 - Taylor & Francis
HIV-1 infection in human beings has been an outcome of cross-species transmission event
of simian immunodeficiency virus from chimpanzees (SIVcpz). Present study reveals …

Unusual cysteine content in V1 region of gp120 from an elite suppressor that produces broadly neutralizing antibodies

JM Hutchinson, KA Mesa, DL Alexander, B Yu… - Frontiers in …, 2019 - frontiersin.org
Although it is now possible to produce recombinant HIV envelope glycoproteins (Envs) with
epitopes recognized by the 5–6 major classes of broadly neutralizing antibodies (bNAbs) …

Evolutionary dynamics of codon usages for peste des petits ruminants virus

X Wang, J Sun, L Lu, F Pu, D Zhang… - Frontiers in Veterinary …, 2022 - frontiersin.org
Peste des petits ruminants virus (PPRV) is an important agent of contagious, acute and
febrile viral diseases in small ruminants, while its evolutionary dynamics related to codon …

Evolutionary divergence of TLR9 through ancestral sequence reconstruction

M Ghosh, S Basak, S Dutta - Immunogenetics, 2024 - Springer
The transmembrane pattern recognition receptor, Toll-like receptor (TLR), are best known for
their roles in innate immunity via recognition of pathogen and initiation of signaling …

Underlying selection for the diversity of spike protein sequences of SARS‐CoV‐2

M Ghosh, S Basak, S Dutta - IUBMB life, 2022 - Wiley Online Library
The global spread of SARS‐CoV‐2 is fast moving and has caused a worldwide public health
crisis. In the present article, we analyzed spike protein sequences of SARS‐CoV‐2 …

Resistance to human immunodeficiency virus infection: a rare but neglected state

C Tamalet, C Devaux, G Dubourg… - Annals of the New York …, 2021 - Wiley Online Library
The natural history of human immunodeficiency virus (HIV) infection is well understood. In
most individuals sexually exposed to HIV, the risk of becoming infected depends on the viral …