Astrocytes contribute to the complex cellular pathology of Alzheimer's disease (AD).
Neurons and astrocytes function in close collaboration through neurotransmitter recycling …

The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …

Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β and tau. We
previously reported that administration of bone marrow mesenchymal stem cells (BM-MSCs) …

Excitotoxicity is a phenomenon that describes the toxic actions of excitatory
neurotransmitters, primarily glutamate, where the exacerbated or prolonged activation of …

Microglia and astrocytes play essential roles in the central nervous system contributing to
many functions including homeostasis, immune response, blood–brain barrier maintenance …

Reactive astrocytes were identified as a component of senile amyloid plaques in the cortex
of Alzheimer's disease (AD) patients several decades ago. However, their role in AD …

Neurodegeneration is a major age-related pathology. Cognitive decline is characteristic of
patients with Alzheimer's and related dementias and cancer patients after chemo-or radio …

Tauopathies are a heterogenous class of diseases characterized by cellular accumulation of
aggregated tau and include diseases such as Alzheimer's disease (AD), progressive …

The nervous system plays a critical role in maintaining whole-organism homeostasis;
neurons experiencing mitochondrial stress can coordinate the induction of protective cellular …