Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD)
frequently occur together and their coexistence is associated with worse outcomes than …

Coenzyme Q (CoQ) is present in all cells and membranes and in addition to be a member of
the mitochondrial respiratory chain it has also several other functions of great importance for …

Once thought to result from passive precipitation of calcium and phosphate, it now appears
that vascular calcification is a consequence of tightly regulated processes that culminate in …

Background Retrospective studies have shown that statins decrease the rate and severity of
exacerbations, the rate of hospitalization, and mortality in chronic obstructive pulmonary …

The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors or statins are potent
inhibitors of cholesterol biosynthesis. Several large clinical trials have demonstrated the …

The importance of reactive oxygen species (ROS) in vascular physiology and pathology is
becoming increasingly evident. All cell types in the vascular wall produce ROS derived from …

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the Western
world. Its incidence has been increasing lately in developing countries. Several lines of …

Background—Inflammatory processes have fundamental roles in stroke in both the etiology
of ischemic cerebrovascular disease and the pathophysiology of cerebral ischemia. We …

Statins or 3-hydroxy-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors not only
prevents the synthesis of cholesterol biosynthesis but also inhibits the synthesis of essential …

Increased oxidative stress plays an important role in the pathophysiology of cardiovascular
diseases such as hypertension, atherosclerosis, diabetes, cardiac hypertrophy, heart failure …