Half a century of amyloids: past, present and future

PC Ke, R Zhou, LC Serpell, R Riek… - Chemical Society …, 2020 - pubs.rsc.org
Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …

Amyloid assembly and disassembly

E Chuang, AM Hori, CD Hesketh… - Journal of Cell …, 2018 - journals.biologists.com
Amyloid fibrils are protein homopolymers that adopt diverse cross-β conformations. Some
amyloid fibrils are associated with the pathogenesis of devastating neurodegenerative …

[HTML][HTML] Molecular characterisation of csgA gene among ESBL strains of A. baumannii and targeting with essential oil compounds from Azadirachta indica

AI Jaisankar, ASS Girija, S Gunasekaran… - Journal of King Saud …, 2020 - Elsevier
Objectives A. baumannii is considered as a “red alert” nosocomial human pathogen and
exhibits an extensive antibiotic resistance spectrum. The biofilm formation mediated by the …

Two decades of studying functional amyloids in microorganisms

SA Levkovich, E Gazit, DL Bar-Yosef - Trends in Microbiology, 2021 - cell.com
In the past two decades, amyloids, typically associated with human diseases, have been
described to play various functional roles in nearly all life forms. The structural and functional …

[HTML][HTML] Bacterial biofilm inhibitors: An overview

VC Kalia, SKS Patel, JK Lee - Ecotoxicology and Environmental Safety, 2023 - Elsevier
Bacteria that cause infectious diseases adopt biofilms as one of their most prevalent
lifestyles. Biofilms enable bacteria to tolerate environmental stress and evade antibacterial …

[HTML][HTML] Functional amyloid and other protein fibers in the biofilm matrix

E Erskine, CE MacPhee, NR Stanley-Wall - Journal of Molecular Biology, 2018 - Elsevier
Biofilms are ubiquitous in the natural and man-made environment. They are defined as
microbes that are encapsulated in an extracellular, self-produced, biofilm matrix. Growing …

Co‐delivery of an amyloid‐disassembling polyphenol cross‐linked in a micellar shell with core‐loaded antibiotics for balanced biofilm dispersal and killing

S Tian, HC van der Mei, Y Ren… - Advanced Functional …, 2022 - Wiley Online Library
Amyloid‐fibers help to maintain the structure of infectious biofilms. Disassembly of amyloid‐
fibers contributes to biofilm‐dispersal in the blood‐circulation, from which bacteria should be …

Microbial nanowires for sustainable electronics

MJ Guberman-Pfeffer, NM Dorval Courchesne… - Nature Reviews …, 2024 - nature.com
Microbial protein nanowires are emerging as an alternative to abiotic nanowires for
electronics applications. Microbial nanowires are sustainably produced, robust, non-toxic …

[HTML][HTML] Stress-responsive regulation of extracellular proteostasis

JS Mesgarzadeh, JN Buxbaum, RL Wiseman - Journal of Cell Biology, 2022 - rupress.org
Genetic, environmental, and aging-related insults can promote the misfolding and
subsequent aggregation of secreted proteins implicated in the pathogenesis of numerous …

Accelerated amyloid beta pathogenesis by bacterial amyloid FapC

I Javed, Z Zhang, J Adamcik… - Advanced …, 2020 - Wiley Online Library
The gut–brain axis has attracted increasing attention in recent years, fueled by accumulating
symptomatic, physiological, and pathological findings. In this study, the aggregation and …