X Li, W Li, M Zeng, R Zheng, M Li - Briefings in bioinformatics, 2020 - academic.oup.com
Genes that are thought to be critical for the survival of organisms or cells are called essential genes. The prediction of essential genes and their products (essential proteins) is of great …
Background and scope Nowadays, centrality analysis has become a principal method for identifying essential proteins in biological networks. Here we present CytoNCA, a Cytoscape …
Proteins differentially interact with each other across cellular states and conditions, but an efficient proteome-wide strategy to monitor them is lacking. We report the application of …
G Liu, L Wong, HN Chua - Bioinformatics, 2009 - academic.oup.com
Motivation: Protein complexes are important for understanding principles of cellular organization and function. High-throughput experimental techniques have produced a large …
RJ Schaefer, JM Michno, J Jeffers, O Hoekenga… - The Plant …, 2018 - academic.oup.com
Genome-wide association studies (GWAS) have identified loci linked to hundreds of traits in many different species. Yet, because linkage equilibrium implicates a broad region …
J Wang, J Zhong, G Chen, M Li, F Wu… - IEEE/ACM transactions …, 2014 - ieeexplore.ieee.org
Cluster analysis of biological networks is one of the most important approaches for identifying functional modules and predicting protein functions. Furthermore, visualization of …
J Wang, M Li, J Chen, Y Pan - IEEE/ACM Transactions on …, 2010 - ieeexplore.ieee.org
As advances in the technologies of predicting protein interactions, huge data sets portrayed as networks have been available. Identification of functional modules from such networks is …
H Feng, D Jin, J Li, Y Li, Q Zou… - Briefings in Bioinformatics, 2023 - academic.oup.com
Numerous experimental studies have indicated that alteration and dysregulation in mircroRNAs (miRNAs) are associated with serious diseases. Identifying disease-related …
B Chen, W Fan, J Liu, FX Wu - Briefings in bioinformatics, 2014 - academic.oup.com
Cellular processes are typically carried out by protein complexes and functional modules. Identifying them plays an important role for our attempt to reveal principles of cellular …