Clinical prognostic factors in pediatric adrenocortical tumors: a meta‐analysis

E Zambaiti, M Duci, F De Corti, P Gamba… - Pediatric blood & …, 2021 - Wiley Online Library
Pediatric adrenocortical tumors (ACT) are rare and sometimes aggressive malignancies, but
there is no consensus on the outcome predictors in children. A systematic search of …

Adrenocortical carcinoma in childhood: A systematic review

M Riedmeier, B Decarolis, I Haubitz, S Müller… - Cancers, 2021 - mdpi.com
Simple Summary Pediatric adrenocortical tumors are rare. Little information is available on
the incidence, risk factors, prognostic factors, treatment, and overall survival. In this …

Pituitary tumors contain a side population with tumor stem cell-associated characteristics

F Mertens, L Gremeaux, J Chen, Q Fu… - Endocrine-Related …, 2015 - erc.bioscientifica.com
Pituitary adenomas cause significant endocrine and mass-related morbidity. Little is known
about the mechanisms that underlie pituitary tumor pathogenesis. In the present study, we …

Low expression of HLA‐DRA, HLA‐DPA1, and HLA‐DPB1 is associated with poor prognosis in pediatric adrenocortical tumors (ACT)

FA Leite, RCP Lira, PF Fedatto… - Pediatric blood & …, 2014 - Wiley Online Library
Background Low expression of HLA class II antigens has been associated with more
aggressive disease in several human malignancies including adult adrenocortical tumors …

Vitamin D receptor activation is a feasible therapeutic target to impair adrenocortical tumorigenesis

AC Bueno, CB More, J Marrero-Gutiérrez… - Molecular and Cellular …, 2022 - Elsevier
Objective To evaluate the therapeutic potential of vitamin D receptor (VDR) signaling in
adrenocortical carcinoma (ACC) cells. Methods We evaluated VDR's methylation pattern in …

Dihydroartemisinin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cell by Upregulating Tumor Necrosis Factor via JNK/NF‐κB …

L Wu, Y Cheng, J Deng, W Tao… - … and Alternative Medicine, 2019 - Wiley Online Library
Background. Dihydroartemisinin (DHA) is a predominant compound in Artemisia annua L.,
and it has been shown to inhibit tumorigenesis. Methods. In this study, the antitumor …

Triptolide inhibits the function of TNF-α in osteoblast differentiation by inhibiting the NF-κB signaling pathway

SP Liu, GD Wang, XJ Du, G Wan… - Experimental and …, 2017 - spandidos-publications.com
Chronic inflammation often delays fracture healing or leads to bone nonunion. Effectively
suppressing pathological inflammation is crucial for fracture healing or bone remodeling …

Apoptosis regulation in adrenocortical carcinoma

SS Pereira, MP Monteiro, SR Antonini… - Endocrine …, 2019 - ec.bioscientifica.com
Apoptosis evading is a hallmark of cancer. Tumor cells are characterized by having an
impaired apoptosis signaling, a fact that deregulates the balance between cell death and …

Low PRKAB2 Expression Is Associated with Poor Outcomes in Pediatric Adrenocortical Tumors, and Treatment with Rottlerin Increases the PRKAB2 Level and …

AET Xavier, LC Veronez, LFP Nagano, CAP Correa… - Cancers, 2024 - mdpi.com
Simple Summary Adrenocortical tumors are rare neoplasms with an uncertain prognosis. A
greater understanding of the biology of these tumors will allow new therapeutic targets to be …

Analysis of miR-483-3p and miR-630 expression profile in pediatric adrenocortical tumors and the effect of their modulation on adrenal tumorigenesis in vitro

CAP Corrêa, AF Andrade, LC Veronez… - Molecular and Cellular …, 2024 - Elsevier
Pediatric adrenocortical tumors (ACT) are rare aggressive neoplasms with heterogeneous
prognosis. MicroRNA (miRNA) signatures have been associated with cancer diagnosis …