Parallelization of MAFFT for large-scale multiple sequence alignments

T Nakamura, KD Yamada, K Tomii, K Katoh - Bioinformatics, 2018 - academic.oup.com
We report an update for the MAFFT multiple sequence alignment program to enable parallel
calculation of large numbers of sequences. The G-INS-1 option of MAFFT was recently …

A survey on the algorithm and development of multiple sequence alignment

Y Zhang, Q Zhang, J Zhou, Q Zou - Briefings in bioinformatics, 2022 - academic.oup.com
Multiple sequence alignment (MSA) is an essential cornerstone in bioinformatics, which can
reveal the potential information in biological sequences, such as function, evolution and …

Parallel protein multiple sequence alignment approaches: a systematic literature review

SH Almanza-Ruiz, A Chavoya… - The Journal of …, 2023 - Springer
Multiple sequence alignment approaches refer to algorithmic solutions for the alignment of
biological sequences. Since multiple sequence alignment has exponential time complexity …

Structural Basis for E. coli Penicillin Binding Protein (PBP) 2 Inhibition, a Platform for Drug Design

N Levy, JM Bruneau, E Le Rouzic… - Journal of Medicinal …, 2019 - ACS Publications
Penicillin-binding proteins (PBPs) are the targets of the β-lactams, the most successful class
of antibiotics ever developed against bacterial infections. Unfortunately, the worldwide and …

Multiple Origins and Specific Evolution of CRISPR/Cas9 Systems in Minimal Bacteria (Mollicutes)

T Ipoutcha, I Tsarmpopoulos, V Talenton… - Frontiers in …, 2019 - frontiersin.org
CRISPR/Cas systems provide adaptive defense mechanisms against invading nucleic acids
in prokaryotes. Because of its interest as a genetic tool, the Type II CRISPR/Cas9 system …

Parallel feature selection for distributed-memory clusters

J González-Domínguez, V Bolón-Canedo, B Freire… - Information …, 2019 - Elsevier
Feature selection is nowadays an extremely important data mining stage in the field of
machine learning due to the appearance of problems of high dimensionality. In the literature …

[HTML][HTML] Comparative landscape of alternative splicing in fruit plants

G Sablok, B Powell, J Braessler, F Yu, XJ Min - Current Plant Biology, 2017 - Elsevier
Alternative splicing (AS) has played a major role in defining the protein diversity, which
could be linked to phenotypic alternations. It is imperative to have a comparative resolution …

Hybrid approach to structure modeling of the histamine H3 receptor: Multi-level assessment as a tool for model verification

J Jończyk, B Malawska, M Bajda - PLoS One, 2017 - journals.plos.org
The crucial role of G-protein coupled receptors and the significant achievements associated
with a better understanding of the spatial structure of known receptors in this family …

PASTASpark: multiple sequence alignment meets Big Data

JM Abuín, TF Pena, JC Pichel - Bioinformatics, 2017 - academic.oup.com
Motivation One basic step in many bioinformatics analyses is the multiple sequence
alignment. One of the state-of-the-art tools to perform multiple sequence alignment is PASTA …

Fame: fast and memory efficient multiple sequences alignment tool through compatible chain of roots

E Naznooshsadat, P Elham, SZ Ali - Bioinformatics, 2020 - academic.oup.com
Motivation Multiple sequence alignment (MSA) is important and challenging problem of
computational biology. Most of the existing methods can only provide a short length multiple …