Tumor microenvironment-responsive manganese-based nanomaterials for cancer treatment

H Fan, Z Guo - Coordination Chemistry Reviews, 2023 - Elsevier
Tumor microenvironment (TME), which characteristically displays hypoxia,
immunosuppression, reprogramming metabolism and mild acidity, has been considered as …

[HTML][HTML] Lipidic lyotropic liquid crystals: Insights on biomedical applications

G Blanco-Fernández, B Blanco-Fernandez… - Advances in Colloid and …, 2023 - Elsevier
Liquid crystals (LCs) possess unique physicochemical properties, translatable into a wide
range of applications. To date, lipidic lyotropic LCs (LLCs) have been extensively explored …

Competing endogenous RNA networks as biomarkers in neurodegenerative diseases

L Moreno-García, T López-Royo, AC Calvo… - International journal of …, 2020 - mdpi.com
Protein aggregation is classically considered the main cause of neuronal death in
neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration …

Manganese-induced neurodegenerative diseases and possible therapeutic approaches

AC Martins Jr, P Gubert, GR Villas Boas… - Expert review of …, 2020 - Taylor & Francis
Introduction Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's
disease, Huntington's disease, amyotrophic lateral sclerosis and prion disease represent …

Neuroprotective effect of phytoconstituents via nanotechnology for treatment of Alzheimer diseases

D Paramanick, VD Singh, VK Singh - Journal of Controlled Release, 2022 - Elsevier
Alzheimer's disease (AD) is a neurological condition characterised by cognitive and
behavioural dysfunction. The presence of the blood brain barrier (BBB), which prevents …

Role of flavonoids in neurodegenerative diseases: limitations and future perspectives

G Maan, B Sikdar, A Kumar, R Shukla… - Current Topics in …, 2020 - ingentaconnect.com
Background: Flavonoids, a group of natural dietary polyphenols, are known for their
beneficial effects on human health. By virtue of their various pharmacological effects, like …

Matrix metalloproteinase-responsive mesoporous silica nanoparticles cloaked with cleavable protein for “self-actuating” on-demand controlled drug delivery for cancer …

K Vaghasiya, E Ray, A Sharma, OP Katare… - ACS Applied Bio …, 2020 - ACS Publications
The tumour site-specific stimulus responsiveness of smart drug delivery systems gives a
unique system for effective therapeutic delivery with reduced toxic effects of conventional …

[HTML][HTML] Hepatoprotective effect of pinostrobin against thioacetamide-induced liver cirrhosis in rats

SH Shareef, MH Al-Medhtiy, AS Al Rashdi… - Saudi Journal of …, 2023 - Elsevier
The study in vivo assessed the effect of pinostrobin on the histology, immunohistochemistry,
and biochemical parameters of thioacetamide (TAA) induced liver cirrhosis in Sprague …

Progress and challenges of lyotropic liquid crystalline nanoparticles for innovative therapies

AVP Silvestrini, BW Debiasi, FG Praça… - International Journal of …, 2022 - Elsevier
Since the late 20th century, we have witnessed a growing and substantial advance in
nanomedicine, in part due to the development of multifunctional and multimodal …

Nanotechnological approaches for targeting amyloid-β aggregation with potential for neurodegenerative disease therapy and diagnosis

R Shukla, A Singh, M Handa, SJS Flora… - Drug Discovery …, 2021 - Elsevier
Neurodegenerative disorders can arise as a result of amyloid-β production and misfolding of
its protein. The complex anatomy of the brain and the unresolved mechanics of the central …