Minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA)
M Sharma, E Huber, E Arnesdotter, HP Behrsing… - Archives of …, 2024 - Springer
Standard information reporting helps to ensure that assay conditions and data are
consistently reported and to facilitate inter-laboratory comparisons. Here, we present …
consistently reported and to facilitate inter-laboratory comparisons. Here, we present …
Nanoparticle Interactions with the Blood Brain Barrier: Insights from Drosophila and Implications for Human Astrocyte Targeted Therapies
This review explores the intricate connections between Drosophila models and the human
blood-brain barrier (BBB) with nanoparticle-based approaches for neurological treatment …
blood-brain barrier (BBB) with nanoparticle-based approaches for neurological treatment …
[HTML][HTML] Advances in Trans-Epithelial Electrical Resistance (TEER) monitoring integration in an Intestinal Barrier-on-Chip (IBoC) platform with microbubbles-tolerant …
L Giampetruzzi, L Blasi, A Barca, E Sciurti… - Sensing and Bio …, 2022 - Elsevier
Trans-epithelial resistance (TEER) is one of the most widely performed analysis in vitro
methods for monitoring barrier tissue development, formation and functional maturation. It is …
methods for monitoring barrier tissue development, formation and functional maturation. It is …
[HTML][HTML] Towards a gold standard functional readout to characterize In Vitro lung barriers
The development of biomimetic in vitro lung models as an alternative to animal studies is
urgent to improve the predictability of the pharmacokinetics of potential new drugs. For …
urgent to improve the predictability of the pharmacokinetics of potential new drugs. For …
Application of blood brain barrier models in pre-clinical assessment of glioblastoma-targeting CAR-T based immunotherapies
J Huang, YB Li, C Charlebois, T Nguyen, Z Liu… - Fluids and Barriers of …, 2022 - Springer
Human blood brain barrier (BBB) models derived from induced pluripotent stem cells
(iPSCs) have become an important tool for the discovery and preclinical evaluation of …
(iPSCs) have become an important tool for the discovery and preclinical evaluation of …
Novel naringin tablet formulations of agro-resides based nano/micro crystalline cellulose with neuroprotective and Alzheimer ameliorative potentials
WA Helmy, TIM Ragab, BM Salama, M Basha… - International Journal of …, 2023 - Elsevier
This study aimed to prepare micro/nanocrystalline cellulose-loaded naringin (NAR) tablets
and evaluate their neuro-protective/therapeutic potentials in Alzheimer's disease (AD) …
and evaluate their neuro-protective/therapeutic potentials in Alzheimer's disease (AD) …
17-Oxime ethers of oxidized ecdysteroid derivatives modulate oxidative stress in human brain endothelial cells and dose-dependently might protect or damage the …
M Vágvölgyi, D Laczkó, AR Santa-Maria, JP Vigh… - Plos one, 2024 - journals.plos.org
20-Hydroxyecdysone and several of its oxidized derivatives exert cytoprotective effect in
mammals including humans. Inspired by this bioactivity of ecdysteroids, in the current study …
mammals including humans. Inspired by this bioactivity of ecdysteroids, in the current study …
Aβ42 treatment of the brain side reduced the level of flotillin from endothelial cells on the blood side via FGF-2 signaling in a blood–brain barrier model
T Nakamura, T Hashita, Y Chen, Y Gao, Y Sun, S Islam… - Molecular Brain, 2023 - Springer
Our previous study showed that the flotillin level is decreased in the blood of patients with
Alzheimer's disease (AD) when compared to that of patients with non-AD and vascular …
Alzheimer's disease (AD) when compared to that of patients with non-AD and vascular …
Wnt7a decreases brain endothelial barrier function via β-catenin activation
N Manukjan, S Chau, F Caiment… - Molecular …, 2024 - Springer
The blood-brain barrier consists of tightly connected endothelial cells protecting the brain's
microenvironment from the periphery. These endothelial cells are characterized by specific …
microenvironment from the periphery. These endothelial cells are characterized by specific …
[PDF][PDF] Generation and characterization of COL4A1 small vessel disease mutations in a human iPSC model
J Kroeger - 2023 - edoc.ub.uni-muenchen.de
Cerebral small vessel disease (cSVD) is responsible for 1 out of every 4 strokes and
contributes to half of the cases of dementia. Despite its burden to society, there are currently …
contributes to half of the cases of dementia. Despite its burden to society, there are currently …