Progress in the mechanism and targeted drug therapy for COPD

C Wang, J Zhou, J Wang, S Li, A Fukunaga… - … and Targeted Therapy, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …

Oxidative stress in aging human skin

M Rinnerthaler, J Bischof, MK Streubel, A Trost… - Biomolecules, 2015 - mdpi.com
Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging
and even more for extrinsic aging. Although the results are quite different in dermis and …

Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases

A Bhattacharyya, R Chattopadhyay… - Physiological …, 2014 - journals.physiology.org
Reactive oxygen species (ROS) are generated as by-products of normal cellular metabolic
activities. Superoxide dismutase, glutathione peroxidase, and catalase are the enzymes …

Nanoparticles in medicine: a focus on vascular oxidative stress

MD Mauricio, S Guerra-Ojeda… - Oxidative Medicine …, 2018 - Wiley Online Library
Nanotechnology has had a significant impact on medicine in recent years, its application
being referred to as nanomedicine. Nanoparticles have certain properties with biomedical …

Physiological functions of thioredoxin and thioredoxin reductase

ESJ Arnér, A Holmgren - European journal of biochemistry, 2000 - Wiley Online Library
Thioredoxin, thioredoxin reductase and NADPH, the thioredoxin system, is ubiquitous from
Archea to man. Thioredoxins, with a dithiol/disulfide active site (CGPC) are the major cellular …

[HTML][HTML] SIRT3-mediated deacetylation of PRDX3 alleviates mitochondrial oxidative damage and apoptosis induced by intestinal ischemia/reperfusion injury

Z Wang, R Sun, G Wang, Z Chen, Y Li, Y Zhao, D Liu… - Redox biology, 2020 - Elsevier
Abstract Background Hydrogen peroxide (H 2 O 2)-induced mitochondrial oxidative damage
is critical to intestinal ischemia/reperfusion (I/R) injury, and PRDX3 is an efficient H 2 O 2 …

Role of oxidative modifications in atherosclerosis

R Stocker, JF Keaney Jr - Physiological reviews, 2004 - journals.physiology.org
This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

PLANT MITOCHONDRIA AND OXIDATIVE STRESS: Electron Transport, NADPH Turnover, and Metabolism of Reactive Oxygen Species

IM Møller - Annual review of plant biology, 2001 - annualreviews.org
▪ Abstract The production of reactive oxygen species (ROS), such as O2− and H2O2, is an
unavoidable consequence of aerobic metabolism. In plant cells the mitochondrial electron …

Male infertility: the effect of natural antioxidants and phytocompounds on seminal oxidative stress

M Adewoyin, M Ibrahim, R Roszaman, ML Md Isa… - Diseases, 2017 - mdpi.com
Defective sperm function has been identified as the most common cause of infertility. The
objective of this study was to review recent findings on the effects of various antioxidants on …

Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

B Halliwell - Drugs & aging, 2001 - Springer
Free radicals and other so-called 'reactive species' are constantly produced in the brain in
vivo. Some arise by 'accidents of chemistry', an example of which may be the leakage of …