Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs

KU Khan, MU Minhas, SF Badshah, M Suhail, A Ahmad… - Life Sciences, 2022 - Elsevier
Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …

Stimulus-responsive polymeric nanogels as smart drug delivery systems

S Hajebi, N Rabiee, M Bagherzadeh, S Ahmadi… - Acta biomaterialia, 2019 - Elsevier
Nanogels are three-dimensional nanoscale networks formed by physically or chemically
cross-linking polymers. Nanogels have been explored as drug delivery systems due to their …

A review on wound dressings: Antimicrobial agents, biomaterials, fabrication techniques, and stimuli-responsive drug release

E Naseri, A Ahmadi - European Polymer Journal, 2022 - Elsevier
Skin, the largest organ of the body, protects the inner organs against the ambient
environment, and it is prone to internal and external injuries in the form of wounds. The …

Nanocarriers for skin applications: where do we stand?

N Tiwari, ER Osorio‐Blanco, A Sonzogni… - Angewandte Chemie …, 2022 - Wiley Online Library
Skin penetration of active molecules for treatment of diverse diseases is a major field of
research owing to the advantages associated with the skin like easy accessibility, reduced …

Polymer-based smart drug delivery systems for skin application and demonstration of stimuli-responsiveness

L Van Gheluwe, I Chourpa, C Gaigne, E Munnier - Polymers, 2021 - mdpi.com
Progress in recent years in the field of stimuli-responsive polymers, whose properties
change depending on the intensity of a signal, permitted an increase in smart drug delivery …

Recent developments in stimuli-responsive polymer nanogels for drug delivery and diagnostics: A review

NK Preman, RR Barki, A Vijayan, SG Sanjeeva… - European Journal of …, 2020 - Elsevier
Polymer nanogels (NGs) are water-swellable, cross-linked 3D network structures with size
typically range from 1 to 1000 nm. Especially, biocompatible and “smart” NGs engineered …

Dual anticancer drug delivery of D-galactose-functionalized stimuli-responsive nanogels for targeted therapy of the liver hepatocellular carcinoma

M Pooresmaeil, H Namazi, R Salehi - European Polymer Journal, 2022 - Elsevier
In the current research work for the first time, we designed and fabricated a new double-
responsive (pH and temperature) and photoluminescent nanogels capped with D-galactose …

A perspective on the applications of functionalized nanogels: promises and challenges

F Pinelli, M Saadati, EN Zare, P Makvandi… - International …, 2023 - Taylor & Francis
In the last two decades nanogels have emerged as very promising and versatile
biomaterials suitable for a wide range of applications. Their features such as large surface …

Application of nanogels as drug delivery systems in multicellular spheroid tumor model

ED Abdolahinia, G Barati, Z Ranjbar-Navazi… - Journal of Drug Delivery …, 2022 - Elsevier
Nanogels have piqued the interest of researchers as nanoscopic drug delivery systems,
especially for site-specific or time-controlled delivery of therapeutic mediators. A wide range …

Environmental stimulus-responsive mesoporous silica nanoparticles as anticancer drug delivery platforms

H Zhao, Y Li, J Chen, J Zhang, Q Yang, J Cui… - Colloids and Surfaces B …, 2024 - Elsevier
Currently, cancer poses a significant health challenge in the medical community. Traditional
chemotherapeutic agents are often accompanied by toxic side effects and limited …