Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN) is a predominantly drug-
induced disease, with a mortality rate of 15–20%, that engages the expertise of multiple …

Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the most
severe cutaneous adverse reactions that are typically drug-induced in adults. Both SJS and …

Severe cutaneous adverse reactions (SCARs), which include Stevens–Johnson syndrome
and toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (also …

Severe cutaneous adverse reactions to drugs (SCARs) are rare but life‐threatening delayed
allergies. While they primarily affect the skin, they can also affect internal organs …

Decreased epidermal high‐mobility group box 1 (HMGB1) expression is an early marker of
epidermal injury in Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) …

Biologics, including monoclonal antibodies (mAb), have proved to be effective and
successful therapeutic agents, particularly in the treatment of cancer and immune …

Drug-induced delayed hypersensitivity reactions (DHRs) is still a clinical and healthcare
burden in every country. Increasing reports of DHRs have caught our attention to explore the …

Rationale and patient concerns Toxic epidermal necrolysis (TEN) and Stevens-Johnson
syndrome (SJS) are severe drug-induced skin reactions associated with a high mortality …

Introduction Immune-related epidermal necrolysis (irEN), including Stevens-Johnson
Syndrome (SJS) and toxic epidermal necrolysis (TEN), represents a potentially lethal …

Abstract Palmar-plantar erythrodysesthesia (PPE), also known as hand and foot syndrome,
is a condition characterized by inflammation-mediated damage to the skin on the palms and …