Hydrolysis mechanism of the linkers by matrix metalloproteinase-9 using QM/MM calculations

B Chen, Z Kang, E Zheng, Y Liu… - Journal of Chemical …, 2021 - ACS Publications
Activatable cell-penetrating peptides (ACPPs) are known to be able to decrease the
cytotoxicity of cell-penetrating peptide (CPP)-based drug delivery systems. Furthermore …

A systematic computational analysis of human matrix metalloproteinase 13 (MMP-13) crystal structures and structure-based identification of prospective drug …

K Satish Kumar, R Velayutham… - Journal of Biomolecular …, 2020 - Taylor & Francis
Osteoarthritis (OA) is the most common form of arthritis with no available disease-modifying
treatments, and is a major cause of disability. Matrix metalloproteinase 13 (MMP-13) is vital …

Evaluation of a sesquiterpene as possible drug lead against gelatinases via molecular dynamics simulations

S Jamal, A Ahmed, ST Moin - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
Malignant tumors can be targeted by accounting for their metastatic capabilities. Matrix
metalloproteinases (MMPs) are the key players in tumor metastasis facilitating through their …

De-shielding of activatable cell-penetrating peptides: recognizing and releasing in activation process

B Chen, Z Kang, C Yao, B Zhang, Y Liu… - Research on Chemical …, 2021 - Springer
Activatable cell-penetrating peptide (ACPP) would reduce the cytotoxicity of cell-penetrating
peptide (CPP)-based drug delivery system by shielding the negative charge and improve …

[PDF][PDF] Morphological profiling of small molecules for mode-of-action studies using the Cell Painting Assay

T Schneidewind - 2021 - d-nb.info
Morphological Profiling of Small Molecules for Mode-of-Action Studies using the Cell Painting
Assay Page 1 Morphological Profiling of Small Molecules for Mode-of-Action Studies using …