Looking into laminin receptor: critical discussion regarding the non‐integrin 37/67‐kDa laminin receptor/RPSA protein

V DiGiacomo, D Meruelo - Biological Reviews, 2016 - Wiley Online Library
ABSTRACT The 37/67‐kDa laminin receptor (LAMR/RPSA) was originally identified as a 67‐
kDa binding protein for laminin, an extracellular matrix glycoprotein that provides cellular …

Roles of ribosomal proteins in the functioning of translational machinery of eukaryotes

D Graifer, G Karpova - Biochimie, 2015 - Elsevier
Ribosomal proteins (rps) are constituents of ribosomal subunits together with the rRNAs,
and the work of the ribosomes is based on highly cooperative interactions involving these …

Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat

YH Hung, AL Carreiro, KK Buhman - … Acta (BBA)-Molecular and Cell Biology …, 2017 - Elsevier
Enterocytes, the absorptive cells of the small intestine, mediate efficient absorption of dietary
fat (triacylglycerol, TAG). The digestive products of dietary fat are taken up by enterocytes, re …

Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons

A Bolze, B Boisson, B Bosch… - Proceedings of the …, 2018 - National Acad Sciences
Isolated congenital asplenia (ICA) is the only known human developmental defect
exclusively affecting a lymphoid organ. In 2013, we showed that private deleterious …

Localized translation and sarcomere maintenance requires ribosomal protein SA in mice

R Haddad, O Sadeh, T Ziv, I Erlich… - The Journal of …, 2024 - Am Soc Clin Investig
Cardiomyocyte sarcomeres contain localized ribosomes, but the factors responsible for their
localization and the significance of localized translation are unknown. Using proximity …

Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation

L Vania, TM Rebelo, E Ferreira, SFT Weiss - BMC cancer, 2018 - Springer
Background Cancer remains one of the leading causes of death around the world, where
incidence and mortality rates are at a constant increase. Tumourigenic cells are …

RPSA, a candidate gene for isolated congenital asplenia, is required for pre-rRNA processing and spleen formation in Xenopus

JN Griffin, SB Sondalle, A Robson, EK Mis… - …, 2018 - journals.biologists.com
ABSTRACT A growing number of tissue-specific inherited disorders are associated with
impaired ribosome production, despite the universal requirement for ribosome function …

Ribosomal protein SA-positive neutrophil elicits stronger phagocytosis and neutrophil extracellular trap formation and subdues pro-inflammatory cytokine secretion …

Q Sun, N Li, L Jia, W Guo, H Jiang, B Liu… - Frontiers in …, 2021 - frontiersin.org
Streptococcus suis serotype 2 (SS2), an important zoonotic pathogen that causes
septicemia, arthritis, and irreversible meningitis in pigs and humans, can be transmitted to …

Knockdown of LRP/LR induces apoptosis in pancreatic cancer and neuroblastoma cells through activation of caspases

CJ Chetty, E Ferreira, K Jovanovic, SFT Weiss - Experimental cell research, 2017 - Elsevier
The 37 kDa/67 kDa laminin receptor (LRP/LR) serves various physiological and
pathological roles such as enhancing tumour-related processes including metastasis …

Hydrogen peroxide regulates cell adhesion through the redox sensor RPSA

F Vilas-Boas, A Bagulho, R Tenente… - Free Radical Biology …, 2016 - Elsevier
To become metastatic, a tumor cell must acquire new adhesion properties that allow
migration into the surrounding connective tissue, transmigration across endothelial cells to …