A survey of EPA/OPP and open literature on selected pesticide chemicals: III. Mutagenicity and carcinogenicity of benomyl and carbendazim

NE McCarroll, A Protzel, Y Ioannou, HF Stack… - … Research/Reviews in …, 2002 - Elsevier
The known aneuploidogens, benomyl and its metabolite, carbendazim (methyl 2-
benzimidazole carbamate (MBC)), were selected for the third in a series of ongoing projects …

Advantages and limitations of using fluorescence in situ hybridization for the detection of aneuploidy in interphase human cells

DA Eastmond, M Schuler, DS Rupa - Mutation Research Letters, 1995 - Elsevier
Fluorescence in situ hybridization with chromosome-specific DNA probes is being
increasingly utilized for the detection of chromosome aberrations induced in vitro and in vivo …

Detection of aneuploidy and aneuploidy-inducing agents in human lymphocytes using fluorescence in situ hybridization with chromosome-specific DNA probes

DA Eastmond, D Pinkel - Mutation Research/Environmental Mutagenesis …, 1990 - Elsevier
The feasibility of utilizing fluorescence in situ hybridization with chromosome-specific DNA
probes as the basis of an assay to detect aneuploidy and aneuploidy-inducing agents in …

Griseofulvin

L De Carli, L Larizza - Mutation Research/Reviews in Genetic Toxicology, 1988 - Elsevier
Griseofulvin (GF) is a mycotoxin produced by various species of Penicillium including P.
griseofulvum Dierckx, P. janczewski (P. nigricans) and P. patulum. It is active against …

Toxic effects of griseofulvin: disease models, mechanisms, and risk assessment

S Knasmüller, W Parzefall, C Helma… - Critical reviews in …, 1997 - Taylor & Francis
Griseofulvin (GF) has been in use for more than 30 years as a pharmaceutical drug in
humans for the treatment of dermatomycoses. Animal studies give clear evidence that it …

Age-associated micronuclei containing centromeres and the X chromosome in lymphocytes of women

J Catalán, K Autio, M Wessman, C Lindholm… - … and Genome Research, 1995 - karger.com
Chronological aging of women is clearly associated with an increase in both X-chromosome
loss and micronuclei formation in peripheral lymphocytes. It has been suggested that …

Evaluation of twelve potential aneuploidogenic chemicals by the in vitro human lymphocyte micronucleus assay

L Migliore, M Nieri - Toxicology in vitro, 1991 - Elsevier
Within the framework of the EEC Project on the validation of tests for genomic mutations, 12
chemicals were submitted to the micronucleus assay using in vitro cultured human …

Evalution of benomyl and carbendazim in the vivo aneuploidy/micronucleus assay in BDF1 mouse bone marrow

AM Sarrif, KS Bentley, LJ Fu, RM Neil… - Mutation Research …, 1994 - Elsevier
Benomyl and its active metabolite carbendazim were investigated in BDF1 mouse bone
marrow to establish whether micronuclei induced by these fungicides are caused by …

Chromosome Missegregation and Aneuploidy Induction in Human Peripheral Blood Lymphocytes In vitro by Low Concentrations of Chlorpyrifos, Imidacloprid and α …

V Mužinić, S Ramić, D Želježić - Environmental and molecular …, 2019 - Wiley Online Library
Chlorpyrifos, imidacloprid, and α‐cypermethrin are some of the most widely used
insecticides in contemporary agriculture. However, their low‐dose, nontarget genotoxic …

Evaluation of carbendazim for gene mutations in the Salmonella/Ames plate-incorporation assay: the role of aminophenazine impurities

AM Sarrif, GT Arce, DF Krahn, RM O'Neil… - Mutation Research …, 1994 - Elsevier
Abstract Benomyl (methyl [1-[(butylamino) carbonyl]-1 H-benzimidazol-2-yl] carbamate) and
its major metabolite carbendazim (methyl 2-benzimidazolecarbamate) are major agricultural …