From neural tube to spinal cord: The dynamic journey of the dorsal neuroepithelium

S Ventriglia, C Kalcheim - Developmental Biology, 2024 - Elsevier
In a developing embryo, formation of tissues and organs is remarkably precise in both time
and space. Through cell-cell interactions, neighboring progenitors coordinate their activities …

Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis

H Tawarayama, H Yamada, R Amin… - Scientific Reports, 2018 - nature.com
Hippocampal neurogenesis in the dentate gyrus (DG) is controlled by diffusible molecules
that modulate neurogenic processes, including cell proliferation, differentiation and survival …

A potential inhibitory function of draxin in regulating mouse trunk neural crest migration

S Zhang, Y Su, J Gao, C Zhang, H Tanaka - In Vitro Cellular & …, 2017 - Springer
Draxin is a repulsive axon guidance protein that plays important roles in the formation of
three commissures in the central nervous system and dorsal interneuron 3 (dI3) in the chick …

Draxin inhibits chick trunk neural crest delamination and migration by increasing cell adhesion

J Du, S Zhang, J Zhao, S Li, W Chen… - Development, Growth …, 2021 - Wiley Online Library
The neural crest is a multipotent cell population that migrates extensively to play important
roles during embryonic development. After acquiring motility, trunk neural crest cells …

Draxin-mediated regulation of granule cell progenitor differentiation in the postnatal hippocampal dentate gyrus

H Tawarayama, H Yamada, R Amin, Y Morita-Fujimura… - Neuroscience, 2020 - Elsevier
The hippocampus is characterized by the presence of life-long neurogenesis. To elucidate
the molecular mechanism regulating hippocampal neurogenesis, we studied the functions of …

The chemorepellent draxin is involved in hippocampal mossy fiber projection

H Tawarayama, H Yamada, Y Shinmyo… - Biochemical and …, 2018 - Elsevier
Lamina-specific afferent innervation of the mammalian hippocampus is critical for its
function. We investigated the relevance of the chemorepellent draxin to the laminar …

Olanzapine Increases Neural Chemorepulsant—Draxin Expression in the Adult Rat Hippocampus

A Pałasz, A Suszka-Świtek, J Francikowski… - Pharmaceuticals, 2021 - mdpi.com
Draxin belongs to the family of inhibitory axon-guiding factors that regulate neuronal
migration and axonal spreading in the developing brain. This glycoprotein has recently been …

背侧抑制性轴突导向蛋白的敲减对鸡胚后脑内23C10 阳性神经纤维投射的影响

王滋怡, 张舒涵, 张子韧, 张文文, 胡亚男, 张三兵… - 解剖学报, 2022 - jpxb.bjmu.edu.cn
目的探讨敲减鸡胚后脑内背侧抑制性轴突导向蛋白(draxin) 的表达对23C10
阳性神经纤维投射特性的影响. 方法以碱性磷酸酶(ALP) 融合蛋白与HH21~ 22 …

In utero electroporation-based translating ribosome affinity purification identifies age-dependent mRNA expression in cortical pyramidal neurons

T Huang, LH Nguyen, TV Lin, X Gong, L Zhang… - Neuroscience …, 2019 - Elsevier
We combined translating ribosome affinity purification (TRAP) with in utero electroporation
(IUE), called iTRAP to identify the molecular profile of specific neuronal populations during …

Potential involvement of draxin in the axonal projection of cranial nerves, especially cranial nerve X, in the chick hindbrain

S Zhang, H Cui, L Wang, L Kang… - … of Histochemistry & …, 2016 - journals.sagepub.com
The appropriate projection of axons within the nervous system is a crucial component of the
establishment of neural circuitry. Draxin is a repulsive axon guidance protein. Draxin has …