Advances in HPV‐associated tumor management: therapeutic strategies and emerging insights
With the rapid increase in the incidence of cervical cancer, anal cancer and other cancers,
human papillomavirus (HPV) infection has become a growing concern. Persistent infection …
human papillomavirus (HPV) infection has become a growing concern. Persistent infection …
Circadian rhythm-related genes index: A predictor for HNSCC prognosis, immunotherapy efficacy, and chemosensitivity
H Chi, J Yang, G Peng, J Zhang, G Song, X Xie… - Frontiers in …, 2023 - frontiersin.org
Background Head and neck squamous cell carcinoma (HNSCC) is the most common head
and neck cancer and is highly aggressive and heterogeneous, leading to variable prognosis …
and neck cancer and is highly aggressive and heterogeneous, leading to variable prognosis …
Identification of copper metabolism-related subtypes and establishment of the prognostic model in ovarian cancer
S Zhao, X Zhang, F Gao, H Chi, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Ovarian cancer (OC) is one of the most common and most malignant
gynecological malignancies in gynecology. On the other hand, dysregulation of copper …
gynecological malignancies in gynecology. On the other hand, dysregulation of copper …
Deciphering the role of HPV-mediated metabolic regulation in shaping the tumor microenvironment and its implications for immunotherapy in HNSCC
X Gong, J Xiong, Y Gong, J Zhang, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC), as a complex and variable malignancy,
poses a significant threat to human health. Since the intricate association between HPV and …
poses a significant threat to human health. Since the intricate association between HPV and …
Prognostic signatures of sphingolipids: Understanding the immune landscape and predictive role in immunotherapy response and outcomes of hepatocellular …
X Zhang, J Zhuge, J Liu, Z Xia, H Wang, Q Gao… - Frontiers in …, 2023 - frontiersin.org
Background Hepatocellular carcinoma (HCC) is a complex disease with a poor outlook for
patients in advanced stages. Immune cells play an important role in the progression of HCC …
patients in advanced stages. Immune cells play an important role in the progression of HCC …
Machine learning to construct sphingolipid metabolism genes signature to characterize the immune landscape and prognosis of patients with uveal melanoma
H Chi, G Peng, J Yang, J Zhang, G Song… - Frontiers in …, 2022 - frontiersin.org
Background Uveal melanoma (UVM) is the most common primary intraocular malignancy in
adults and is highly metastatic, resulting in a poor patient prognosis. Sphingolipid …
adults and is highly metastatic, resulting in a poor patient prognosis. Sphingolipid …
By integrating single-cell RNA-seq and bulk RNA-seq in sphingolipid metabolism, CACYBP was identified as a potential therapeutic target in lung adenocarcinoma
P Zhang, S Pei, Z Gong, Y Feng, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a heterogeneous disease with a dismal
prognosis for advanced tumors. Immune-associated cells in the microenvironment …
prognosis for advanced tumors. Immune-associated cells in the microenvironment …
Identification of a novel anoikis‐related gene signature to predict prognosis and tumor microenvironment in lung adenocarcinoma
X Diao, C Guo, S Li - Thoracic Cancer, 2023 - Wiley Online Library
Background Lung adenocarcinoma (LUAD) is the most prevalent histotype of non‐small cell
lung cancer. Anoikis, an alternative form of programmed cell death, plays a pivotal role in …
lung cancer. Anoikis, an alternative form of programmed cell death, plays a pivotal role in …
Revealing the role of regulatory T cells in the tumor microenvironment of lung adenocarcinoma: a novel prognostic and immunotherapeutic signature
P Zhang, X Zhang, Y Cui, Z Gong, W Wang… - Frontiers in …, 2023 - frontiersin.org
Background Regulatory T cells (Tregs), are a key class of cell types in the immune system. In
the tumor microenvironment (TME), the presence of Tregs has important implications for …
the tumor microenvironment (TME), the presence of Tregs has important implications for …
[HTML][HTML] The integrated single-cell analysis developed an immunogenic cell death signature to predict lung adenocarcinoma prognosis and immunotherapy
P Zhang, H Zhang, J Tang, Q Ren, J Zhang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Background: Research on immunogenic cell death (ICD) in lung adenocarcinoma (LUAD)
has been relatively limited. This study aims to create ICD-related signatures for accurate …
has been relatively limited. This study aims to create ICD-related signatures for accurate …