Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Histone post-translational modifications (HPTMs), as one of the core mechanisms of
epigenetic regulation, are garnering increasing attention due to their close association with …

Major depressive disorder (MDD) is a disease associated with many factors; specifically,
environmental, genetic, psychological, and biological factors play critical roles. Recent …

Stressful life events are a major contributor to the development of major depressive disorder.
Environmental perturbations like stress change gene expression in the brain, leading to …

Post-traumatic stress disorder is a prevalent disorder within the USA and worldwide with a
yearly diagnosis rate of 2–4% and affecting women more than men. One of the primary …

Over the past two decades, epigenetic regulation has become a rapidly growing and
influential field in biology and medicine. One key mechanism involves the acetylation and …

Abstract Melanocortin 4 receptor (MC4R), the most important monogenetic cause of human
metabolic disorders, has been of great interest to many researchers in the field of energy …

Chronic unpredictable mild stress (CUMS) method has been introduced as a rodent model
of depression. On the other hand, olanzapine, as an antipsychotic, can induce …

Major depressive disorder (MDD) is one of the most prevalent forms of mental illness also
affecting older adults. Recent evidence suggests a relationship between MDD and …

The addictive use of nicotine contained in tobacco is associated with stressor‐like emotional
and cognitive effects such as anxiety and working memory impairment, and the involvement …