The role of miRNAs in liver diseases: Potential therapeutic and clinical applications

AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-
transcriptionally to regulate gene expression by binding to particular mRNA targets and …

Amplification-free electrochemical biosensor detection of circulating microRNA to identify drug-induced liver injury

A Roychoudhury, JW Dear… - Biosensors and …, 2023 - Elsevier
Drug-induced liver injury (DILI) is a major challenge in clinical medicine and drug
development. There is a need for rapid diagnostic tests, ideally at point-of-care. MicroRNA …

Genetic and Epigenetic Basis of Drug-Induced Liver Injury

S Singh, PK Kumar, JP Kumar, S Tomo… - Seminars in Liver …, 2023 - thieme-connect.com
Drug-induced liver injury (DILI) is a rare but severe adverse drug reaction seen in
pharmacotherapy and a major cause of postmarketing drug withdrawals. Advances in …

A comprehensive review of Dynamic Chemical Labelling on Luminex xMAP technology: a journey towards Drug-Induced Liver Injury testing

A Marín-Romero, S Pernagallo - Analytical Methods, 2023 - pubs.rsc.org
Drug-Induced Liver Injury (DILI) is a grave global adverse event that can result in fatal
consequences, causing drug failures, market withdrawals, and regulatory warnings, leading …

A drop dispenser for simplifying on-farm detection of foodborne pathogens

M Ranjbaran, S Kaur, J Wang, B Raut, MS Verma - PloS one, 2024 - journals.plos.org
Nucleic-acid biosensors have emerged as useful tools for on-farm detection of foodborne
pathogens on fresh produce. Such tools are specifically designed to be user-friendly so that …

The Evolution of Circulating Biomarkers for Use in Acetaminophen/Paracetamol-Induced Liver Injury in Humans: A Scoping Review

MR McGill, SC Curry - Livers, 2023 - mdpi.com
Acetaminophen (APAP) is a widely used drug, but overdose can cause severe acute liver
injury. The first reports of APAP hepatotoxicity in humans were published in 1966, shortly …